Visual responses of neurons in somatosensory cortex of hamsters with experimentally induced retinal projections to somatosensory thalamus.
Visual responses of neurons in somatosensory cortex of hamsters with experimentally induced retinal projections to somatosensory thalamus.
复制标题
仓鼠体感皮层神经元的视觉反应，实验诱导视网膜投射到体感丘脑。
DOI：
10.1073/pnas.86.1.357
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发表时间：
1989
影响因子：
11.1
通讯作者：
Frost,DO
中科院分区：
文献类型：
--
作者：
Métin,C;Frost,DO
这些实验研究了感觉系统中丘脑和皮层结构处理通常与另一个系统相关的模态信息的能力。新生叙利亚仓鼠的视网膜神经节细胞永久地投射到主要的丘脑体感（腹基底）核。当这些动物成年后，在体感觉皮质（腹基底核的主要目标）中进行单个单元的记录。体感觉神经元对不同感受野的视觉刺激作出反应，其反应性质在若干特征上与正常的视觉皮质神经元相似。在正常动物的视觉皮层和手术动物的体感觉皮层中，相同功能类别的神经元以相似的比例出现，神经元对视觉刺激的方向或运动方向的选择性具有可比性。这些结果表明，丘脑核或皮层区域在视觉和体感觉通路的相应水平上对它们的输入执行类似的转换。
These experiments investigate the capacity of thalamic and cortical structures in a sensory system to process information of a modality normally associated with another system. Retinal ganglion cells in newborn Syrian hamsters were made to project permanently to the main thalamic somatosensory (ventrobasal) nucleus. When the animals were adults, single unit recordings were made in the somatosensory cortices, the principal targets of the ventrobasal nucleus. The somatosensory neurons responded to visual stimulation of distinct receptive fields, and their response properties resembled, in several characteristic features, those of normal visual cortical neurons. In the visual cortex of normal animals and the somatosensory cortex of operated animals, the same functional categories of neurons occurred in similar proportions, and the neurons' selectivity for the orientation or direction of movement of visual stimuli was comparable. These results suggest that thalamic nuclei or cortical areas at corresponding levels in the visual and somatosensory pathways perform similar transformations on their inputs.