Attachment of gold nanograins onto colloidal magnetite nanocrystals
Attachment of gold nanograins onto colloidal magnetite nanocrystals
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DOI：
10.1021/cm050280n
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发表时间：
2005-06-28
影响因子：
8.6
通讯作者：
O'Connor, CJ
中科院分区：
文献类型：
--
作者：
Caruntu, D;Cushing, BL;O'Connor, CJ
报道了通过一种简单的两步化学控制法，成功地将2-3 nm的金粒子附着在类似于10 nm的Fe3O4纳米晶上。单个相对单一分散的Fe3O4纳米球形成稳定的胶体甲醇溶液，表面涂覆一种氨基端基硅烷，胶化后在粒子表面产生正电荷，然后用带负电荷的纳米An胶体溶液处理。通过透射电子显微镜、X射线衍射仪、紫外可见光谱、电感耦合等离子体和超导量子干涉磁强计等手段对纳米复合材料的形貌和性能进行了详细的研究。Fe3O4/Au纳米复合材料由于其浓度低、附着的Au颗粒较小，光学性质不明显。此外，胶体Fe3O4/Au纳米复合材料具有很高的抗分离稳定性，并表现出与母体Fe3O4纳米晶相似的磁性。这些新颖的纳米结构通过将生物活性分子与附着的Au纳米颗粒进行化学键合，为将磁性纳米颗粒用于体内生物医学应用开辟了新的机会。
The successful attachment of 2-3 nm gold particles to similar to 10 nm Fe3O4 nanocrystals through a simple, two-step chemically controlled procedure is reported. The surface of individual, relatively monodisperse, Fe3O4 nanospheres forming a stable colloidal methanolic solution is coated with an amino-terminated silane, peptized to induce positive charges on the particles' surfaces and then treated with a colloidal solution of negatively charged An nanoparticles. A detailed investigation by transmission electron microscopy, X-ray diffraction, UV-vis, inductively coupled plasma, and superconducting quantum interference device magnetometry was performed in order to elucidate the morphology and properties of the nanocomposites. Due to their low concentration and small size of the attached Au particles, the optical properties are not observable in the case of the Fe3O4/Au nanocomposites. Additionally, the colloidal Fe3O4/Au nanocomposites are highly stable against separation and exhibit magnetic properties similar to those of the parent Fe3O4 nanocrystals. These novel nanoarchitectures open up new opportunities for the use of magnetite nanoparticles for in-vivo biomedical applications through chemical bonding of bioactive molecules to the attached Au nanoparticles.