THE EFFECT OF IMMOBILIZATION ON COLLAGEN TURNOVER IN CONNECTIVE-TISSUE - A BIOCHEMICAL-BIOMECHANICAL CORRELATION
THE EFFECT OF IMMOBILIZATION ON COLLAGEN TURNOVER IN CONNECTIVE-TISSUE - A BIOCHEMICAL-BIOMECHANICAL CORRELATION
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DOI：
10.3109/17453678208992224
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发表时间：
1982-01-01
期刊：
影响因子：
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通讯作者：
AKESON, WH
中科院分区：
文献类型：
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作者：
AMIEL, D;WOO, SLY;AKESON, WH
固定[兔]膝关节9周导致外侧副韧带的机械性能降低。具体地，韧带刚度在该组织中降低。内侧副韧带（MCL）或髌腱的胶原质量无统计学变化。在固定的内侧副韧带和髌韧带和髌腱中发现胶原周转（合成和降解）增加。刚度降低可能是由于韧带物质本身的变化，而不是组织萎缩的结果。
Immobilization of the [rabbit] knee joint for 9 wk results in a reduction of the mechanical properties in the lateral collateral ligament. Specifically, ligament stiffness is reduced in this tissue. No statistical change in collagen mass was detected for the medial collateral ligament (MCL) or patellar tendon. An increase in collagen turnover (synthesis and degradation) was found in the immobilized medial collateral ligament and patellar ligament and patellar tendon. Stiffness reduction may be due to a change in the ligament substance itself, rather than a result of tissue atrophy.