The Sequence Ontology: a tool for the unification of genome annotations.

The Sequence Ontology: a tool for the unification of genome annotations.
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DOI:
10.1186/gb-2005-6-5-r44
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发表时间:
2005
期刊:
影响因子:
12.3
通讯作者:
--
中科院分区:
生物学1区
文献类型:
--
作者:

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序列本体 (SO) 项目的目标是生成一个结构化受控词汇表,其中包含基因组注释部分的一组通用术语和定义,并描述它们之间的关系。讨论了 SO 构建、设计和使用的细节,特别是关于部分与整体关系的细节,并通过一组果蝇基因组注释证明了 SO 的实用性。序列本体(SO)是基因组注释部分的结构化受控词汇表。 SO 提供了一套通用的术语和定义,将促进基因组数据的交换、分析和管理。因为 SO 严格地处理部分与整体的关系,所以用它描述的数据可以成为自动推理的基础,并且 SO 描述的序列特征的实例可以接受一组称为外延分体算子的逻辑运算。
The goal of the Sequence Ontology (SO) project is to produce a structured controlled vocabulary with a common set of terms and definitions for parts of a genomic annotation, and to describe the relationships among them. Details of SO construction, design and use, particularly with regard to part-whole relationships are discussed and the practical utility of SO is demonstrated for a set of genome annotations from Drosophila melanogaster. The Sequence Ontology (SO) is a structured controlled vocabulary for the parts of a genomic annotation. SO provides a common set of terms and definitions that will facilitate the exchange, analysis and management of genomic data. Because SO treats part-whole relationships rigorously, data described with it can become substrates for automated reasoning, and instances of sequence features described by the SO can be subjected to a group of logical operations termed extensional mereology operators.