Impact of Functional Pruritus Compared with Mild Psoriasis on Quality of Life: A Cross-Sectional Questionnaire Study in Turkey
Impact of Functional Pruritus Compared with Mild Psoriasis on Quality of Life: A Cross-Sectional Questionnaire Study in Turkey
复制标题
DOI：
10.1007/s40257-014-0075-7
复制
发表时间：
2014-08-01
影响因子：
7.3
通讯作者：
Kucukunal, Asli
中科院分区：
文献类型：
--
作者：
Altunay, Ilknur Kivanc;Atis, Guldehan;Kucukunal, Asli
功能性瘙痒症（FP）是一种慢性瘙痒症，本质上是一种躯体形式的疾病，由心因性因素触发。银屑病是一种慢性炎症性皮肤病，可导致严重的美容问题和心理困扰。本研究旨在探讨功能性瘙痒对生活质量的影响，并与轻度银屑病的影响进行比较。共有73例患者（40例银屑病，33例FP）入选本研究。所有参与者都被要求完成皮肤病生活质量指数（DLQI）和世界卫生组织（WHO）生活质量简表（WHOQOL-BREF-TR）。两组患者瘙痒严重程度均采用视觉模拟评分法（VAS）进行主观评价，银屑病严重程度采用银屑病面积和严重程度指数进行评价。记录患者的年龄、性别、受教育程度、病程和用药情况，两组患者的生活质量无显著差异。FP组的VAS值显著较高。FP患者的年龄与WHOQOL-BREF-TR上的身体领域呈负相关，与WHOQOL-BREF-TR上的心理领域呈负相关，与疾病持续时间呈负相关。在银屑病患者中，发现年龄与DLQI评分呈负相关。FP对生活质量的负面影响与轻度银屑病相当。似乎银屑病患者的银屑病病变的可见性和美容问题并不会导致比FP患者更严重的生活质量受损。
Functional pruritus (FP) is a type of chronic pruritus that is a somatoform disease in nature, triggered by psychogenic factors. Psoriasis is a chronic, inflammatory, and pruritic skin disease that causes significant cosmetic problems and psychological distress.In this study, we aimed to investigate the effects of functional pruritus on quality of life and to compare these with the effects of mild psoriasis.A total of 73 patients (40 with psoriasis and 33 with FP) were enrolled into the study. All the participants were asked to complete the Dermatology Life Quality Index (DLQI) and World Health Organization (WHO) Quality of Life, short form, Turkish version (WHOQOL-BREF-TR). Pruritus severity was evaluated subjectively with a visual analog scale (VAS) in both groups, and psoriasis severity was evaluated with the Psoriasis Area and Severity Index. Patients' age, gender, educational status, duration of disease, and medications were recorded.There was no significant difference in quality of life between the two groups. VAS values were significantly higher in the FP group. A negative correlation was found between age and the physical domain on the WHOQOL-BREF-TR, and also between the psychological domain on the WHOQOL-BREF-TR and the duration of the disease in FP patients. In psoriasis patients, a negative correlation was found between age and DLQI scores.FP has a negative impact on quality of life that is comparable to that of mild psoriasis. It seems that the visibility of psoriatic lesions and the cosmetic concerns in psoriasis patients do not result in a more severely impaired quality of life than in patients with FP.