Continued Development of the Nimbus/University of Pittsburgh (UOP) Axial Flow Left Ventricular Assist System
Continued Development of the Nimbus/University of Pittsburgh (UOP) Axial Flow Left Ventricular Assist System
复制标题
Nimbus/匹兹堡大学 (UOP) 轴流左心室辅助系统的持续开发
DOI：
10.1097/00002480-199709000-00045
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发表时间：
1997
期刊：
影响因子：
4.2
通讯作者：
J. Antaki
中科院分区：
文献类型：
--
作者：
D. Thomas;K. Butler;L. Taylor;P. L. Blanc;B. Griffith;R. Kormos;H. Borovetz;P. Litwak;M. Kameneva;Seongjin Choi;G. Burgreen;W. Wagner;Zhongjun J. Wu;J. Antaki
Nimbus和匹兹堡大学(UOP)根据美国国立卫生研究院(NIH)的创新心室辅助系统(IVAS)计划，继续开发完全植入的轴流血泵。该62CC装置的总长度为84 mm，外径为34.5 mm。血泵的内径为12 mm。它被设计成一个完全植入的永久性装置。过去一年的一项关键成就是完成了模型2泵的设计。已经制造了10个这样的泵，并正在进行体外和体内实验，以评估不同材料和液压元件的性能。通过数学建模、计算机模拟以及体外和体内试验，继续努力优化闭环速度控制。利用计算流体力学(CFD)和流动可视化技术对新型液压叶片设计进行了测试。设计了第二代电机，提高了效率。为了支持新的电机，已经完成了一个由表面贴装PC板制造的新的电机控制器。该计划目前在正式的质量保证系统下运行。
Nimbus and the University of Pittsburgh (UOP) have continued the development of a totally implanted axial flow blood pump under the National Institutes of Health (NIH) Innovative Ventricular Assist System (IVAS) program. This 62 cc device has an overall length of 84 mm and an outer diameter of 34.5 mm. The inner diameter of the blood pump is 12 mm. It is being designed to be a totally implanted permanent device. A key achievement during the past year was the completion of the Model 2 pump design. Ten of these pumps have been fabricated and are being used to conduct in vitro and in vivo experiments to evaluate the performance of different materials and hydraulic components. Efforts for optimizing the closed loop speed control have continued using mathematical modeling, computer simulations, and in vitro and in vivo testing. New hydraulic blade designs have been tested using computational fluid dynamics (CFD) and flow visualization. A second generation motor was designed with improved efficiency. To support the new motor, a new motor controller fabricated as a surface mount PC board has been completed. The program is now operating under a formal QA system.