Impact of diabetes on the risk stratification using stress single-photon emission computed tomography myocardial perfusion Imaging in patients with symptoms suggestive of coronary artery disease
Impact of diabetes on the risk stratification using stress single-photon emission computed tomography myocardial perfusion Imaging in patients with symptoms suggestive of coronary artery disease
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DOI：
10.1161/hc5001.100528
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发表时间：
2002-01-01
期刊：
影响因子：
37.8
通讯作者：
Heller, GV
中科院分区：
文献类型：
--
作者：
Giri, S;Shaw, LJ;Heller, GV
背景-冠状动脉疾病可以过早发展，是糖尿病患者的主要死亡原因，因此需要进行无创风险分层。方法和结果：对5个中心接受负荷心肌灌注成像(MPI)的有冠状动脉疾病症状的患者进行前瞻性随访(2.5+/-1.5年)，观察随后发生的心脏性死亡、心肌梗死(MI)和血运重建。负荷MPI结果分为正常或异常(固定或缺血缺陷和1、2或3支血管分布)。4755例患者中，929例(19.5%)为糖尿病患者。尽管糖尿病患者的血管重建率增加，但仍有80例心脏事件(8.6%；39例死亡和41例错失)发生，而非糖尿病组的172例心脏事件(4.5%；69例死亡和103例错失)(P
Background-Coronary artery disease can develop prematurely and is the leading cause of death among diabetics, making noninvasive risk stratification desirable.Methods and Results-Patients with symptoms of coronary artery disease who were undergoing stress myocardial perfusion imaging (MPI) from 5 centers were prospectively followed (2.5 +/- 1.5 years) for the subsequent occurrence of cardiac death, myocardial infarction (MI), and revascularization. Stress MPI results were categorized as normal or abnormal (fixed or ischemic defects and 1, 2, or 3 vessel distribution). Of 4755 patients, 929 (19.5%) were diabetic. Patients with diabetes, despite an increased revascularization rate, had 80 cardiac events (8.6%; 39 deaths and 41 MIs) compared with 172 cardiac events (4.5%; 69 deaths and 103 MIs) in the nondiabetic cohort (P