Omission bias and vaccine rejection by parents of healthy children: Implications for the influenza A/H1N1 vaccination programme

Omission bias and vaccine rejection by parents of healthy children: Implications for the influenza A/H1N1 vaccination programme
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DOI:
10.1016/j.vaccine.2010.04.012
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发表时间:
2010-06-07
期刊:
影响因子:
5.5
通讯作者:
Sevdalis, Nick
Sevdalis, Nick
中科院分区:
医学3区
文献类型:
--
作者:
Brown, Katrina F.;Kroll, J. Simon;Sevdalis, Nick

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自2009年12月以来,英国已向6个月至5岁的健康儿童提供甲型Hi NI流感(“猪流感”)疫苗,尽管约50%的父母计划拒绝接种。这项研究考察了这些父母是否表现出遗漏偏见(倾向于不作为引起的错误,而不是行动引起的错误)。142名家长完成了一份在线问卷,其中他们对(A)发生概率、(B)症状和(C)假想疾病和假想疫苗不良事件的持续时间进行了评分。尽管这些属性在客观上是相同的,但几乎所有的属性在与VAE相关时都明显不如与疾病相关(P<在22个结果中有17个被评为0.01)。这些数据表明,与感染本身相比,任何疫苗在许多父母的意识中都处于劣势,轻微的安全问题可能会对疫苗接种产生不成比例的有害影响。行为科学提供了改善这种偏见的影响的策略,这些策略应该得到进一步的探索。(C)2010爱思唯尔有限公司。保留所有权利。
2009 Hi NI influenza A ("swine flu") vaccine has been offered to healthy UK children aged 6 months-5 years since December 2009, though around 50% of parents plan to reject the vaccine. This study examined whether such parents exhibit omission bias (preference for errors arising from inaction over errors arising from action). One-hundred and forty-two parents completed an online questionnaire in which they rated (a) probability of occurrence, (b) symptoms and (c) duration of a hypothetical disease and a hypothetical vaccine adverse event (VAE). Almost all attributes were rated significantly less favourably when relating to VAE than to disease (p < 0.01 for 17 of 22 outcomes), despite the attributes being objectively identical. These data suggest that any vaccine is at a disadvantage in many parents' consciousness in comparison with the infection itself, and that minor safety concerns could have disproportionately detrimental effects on vaccine uptake. Behavioural science offers strategies to ameliorate the impact of this bias and these should be explored further. (C) 2010 Elsevier Ltd. All rights reserved.