Antecedent biomarkers of Alzheimer's disease: The Adult Children Study

Antecedent biomarkers of Alzheimer's disease: The Adult Children Study
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DOI:
10.1177/0891988705281881
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发表时间:
2005-12-01
影响因子:
2.6
通讯作者:
Morris, JC
Morris, JC
中科院分区:
医学4区
文献类型:
--
作者:
Coats, M;Morris, JC

文献摘要

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华盛顿大学成人儿童研究是一项纵向研究,旨在开发和验证生物标记、成像特征和其他临床前指标。阿尔茨海默病有助于识别患有症状性阿尔茨海默病的高风险个体。两组年龄在 45 岁至 74 岁之间的参与者正在参加成人儿童研究。第 1 组代表至少有 1 名父母患有阿尔茨海默病的成年子女。第 2 组代表父母至少活到 70 岁且没有痴呆症的成年子女。成人儿童研究参与者的参与积极性很高,这项研究需要参与者和研究人员多年的投入才能知道最重要的结果。
The Washington University Adult Children Study is a longitudinal study to develop and validate biological markers, imaging features, and other indicators of preclinical. Alzheimer's disease to aid in identifying individuals at high risk for developing symptomatic Alzheimer's disease. Two groups of participants between the ages of 45 and 74 are being enrolled in the Adult Children Study. Group 1 represents adult children who have at least 1 parent with Alzheimer's disease. Group 2 represents adult children whose parents have lived at least to age 70 without dementia. The Adult Children Study participants have been highly motivated to participate, and this study will require the investment of many years from the participants and the investigators before its most significant results will be known.