Gene transfer strategies for metabolic diseases.
Gene transfer strategies for metabolic diseases.
复制标题
代谢疾病的基因转移策略。
DOI：
10.1007/s00268-002-4061-5
复制
发表时间：
2002
期刊：
影响因子：
--
通讯作者：
McClane,StevenJ
中科院分区：
文献类型：
--
作者：
Raper,StevenE;McClane,StevenJ
Recent advances in molecular genetics and biotechnology will revolutionize the practice of medicine and surgery during the next decade. Surgeons must understand and begin to use the new technologies in the study of surgical biology and patient care. A brief overview of the principles of gene transfer and how this technology is used for treating metabolic disease is presented. Two examples of how recombinant viruses (vectors) can be used to study fundamental biology in the liver and pancreas are given. Familial hypercholesterolemia is used as a paradigm for a clinical gene transfer study and underscores the importance of surgeons in the development of novel therapeutic strategies.
