NONHEMORRHAGIC THALAMIC INFARCTION - CLINICAL, NEUROPSYCHOLOGICAL AND ELECTROPHYSIOLOGICAL FINDINGS IN 4 ANATOMICAL GROUPS DEFINED BY COMPUTERIZED-TOMOGRAPHY

NONHEMORRHAGIC THALAMIC INFARCTION - CLINICAL, NEUROPSYCHOLOGICAL AND ELECTROPHYSIOLOGICAL FINDINGS IN 4 ANATOMICAL GROUPS DEFINED BY COMPUTERIZED-TOMOGRAPHY
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DOI:
10.1093/brain/108.2.485
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发表时间:
1985-01-01
期刊:
影响因子:
14.5
通讯作者:
DAMASIO, AR
DAMASIO, AR
中科院分区:
医学1区
文献类型:
--
作者:
GRAFFRADFORD, NR;DAMASIO, H;DAMASIO, AR

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25例非出血性丘脑梗死患者进行了临床研究,神经心理测试,计算机断层扫描和体感诱发反应(SER)记录。我们的目的是确定是否在这些不同的测试结果将形成不同的症状集群与不同的解剖领域的thalama.Infarction符合丘脑结节动脉领土造成面部麻痹的情绪运动,严重的神经心理缺陷和延迟的SER后P14。符合脚间深动脉领域的梗死引起核上垂直凝视麻痹,严重的神经心理缺陷和延迟的P60成分的SER。符合前脉络膜领域的梗死引起轻偏瘫,中度神经心理缺陷和各种感觉诱发反应。符合整个膝状丘脑区域的梗死患者在P14后有多种方式的感觉丧失,最小的神经心理学缺陷和感觉诱发反应的缺乏。这一区域的缺陷导致了纯粹的半感觉缺失,涉及身体的一部分,用于疼痛和轻触的方式,但不是本体感觉或振动。神经心理学缺陷是罕见的,N32和N60在SER中延迟。
Twenty-five patients with nonhaemorrhagic infarcts of the thalamus were studied clinically and by neuropsychological testing, computerized tomography and somatosensory evoked response (SER) recordings. Our aim was to determine whether the findings in these different tests would form distinct symptom clusters associated with different anatomical territories of the thalamus.Infarction conforming to the tuberothalamic arterial territory caused a facial paresis for emotional movements, severe neuropsychological deficits and a delay of the SER after P14. Infarction conforming to the interpeduncular profundus arterial territory caused a supranuclear vertical gaze paresis, severe neuropsychological deficits and a delay in the P60 component of the SER. Infarction conforming to the anterior choroidal territory caused a hemiparesis, moderate neuropsychological deficits and varied sensory evoked responses. Patients with infarctions conforming to the entire geniculothalamic territory had sensory loss in multiple modalities, minimal neuropsychological deficits and absence of sensory evoked responses after P14. A lacune in this territory caused pure hemisensory loss involving part of the body for the modalities of pain and light touch but not proprioception or vibration. Neuropsychological deficits were uncommon and N32 and N60 were delayed in the SER.