Acquired protein C deficiency following cisplatinum-navelbine administration for locally advanced breast cancer. Case report.
Acquired protein C deficiency following cisplatinum-navelbine administration for locally advanced breast cancer. Case report.
复制标题
局部晚期乳腺癌使用顺铂-长春滨后出现获得性蛋白 C 缺乏症。
DOI：
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发表时间：
1999
影响因子：
0.4
通讯作者：
A. Khalil
中科院分区：
文献类型：
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作者：
A. Taher;A. Shamsseddine;N. Saghir;M. Seoud;F. Mourad;B. Dabajah;A. Khalil
最近有报道称，乳腺癌患者在接受不同的化疗方案后发生血栓事件。这是一例39岁的妇女，被诊断为局部晚期乳腺癌，接受了多种化疗方案。她在开始顺铂-诺维本方案治疗2个月后出现深静脉血栓形成。蛋白C缺乏症是化疗停止后唯一异常的凝血试验。
Thromboembolic events have recently been reported following diverse regimens of chemotherapy for breast cancer. This is a report of a 39-year-old woman, a diagnosed case of locally advanced breast cancer, who received many regimens of chemotherapy. She presented with deep venous thrombosis 2 months after starting the cisplatinum-navelbine regimen. Protein C deficiency was the only abnormal coagulation test that normalized after cessation of chemotherapy.