Precise protein assembly of array structures.
Precise protein assembly of array structures.
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DOI：
10.1039/c6cc04190f
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发表时间：
2016-08
影响因子：
4.9
通讯作者：
Guang Yang;Li-bin Wu;Guosong Chen;Ming Jiang
中科院分区：
文献类型：
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作者：
Guang Yang;Li-bin Wu;Guosong Chen;Ming Jiang
将蛋白质组装成各种具有规则和周期性微观结构的纳米物体，即蛋白质阵列，是材料科学中一个快速发展的领域。由于蛋白质结构的复杂性，在这一领域的报道仍然相当有限。本文综述了利用静电相互作用、金属-配体相互作用、分子识别和蛋白质-蛋白质相互作用等不同驱动力构建蛋白质阵列的研究进展。根据我们的特殊兴趣，我们特别探索了由分子识别驱动的组装。最后，简要讨论了获得的蛋白质阵列的功能。
The assembly of proteins into various nano-objects with regular and periodic microstructures, i.e. protein arrays, is a fast-growing field in materials science. Due to the structural complexity of proteins, reports in this field are still quite limited. In this review, we summarize the recent developments in protein array construction by different driving forces, including electrostatic interactions, metal-ligand interactions, molecular recognition and protein-protein interactions. In line with our particular interest, assemblies driven by molecular recognition are particularly explored. Finally, functionalities of the obtained protein arrays are briefly discussed.