Mechanisms for heart failure in systemic right ventricle

Mechanisms for heart failure in systemic right ventricle
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DOI:
10.1007/s10741-019-09902-1
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发表时间:
2020-07-01
影响因子:
4.6
通讯作者:
Wilson, William
Wilson, William
中科院分区:
医学2区
文献类型:
--
作者:
Andrade, Lauren;Carazo, Matthew;Wilson, William

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主要有两种情况,即先天性矫正型大动脉转位(CC-TGA)和D-大动脉转位(D-TGA)患者接受了心房转位手术。有证据表明,处于全身位置的右室易患心力衰竭。在这篇综述中,我们的目标是探索这两类患者中系统性右心室患者心力衰竭的机制和病理生理学。
There are two predominant scenarios where the right ventricle acts as the systemic ventricle, namely congenitally corrected transposition of the great arteries (CC-TGA) and patients with D-transposition of the great arteries (D-TGA) who have undergone an atrial switch operation. There is evidence that having a right ventricle in the systemic position predisposes to the development of heart failure. In this review, we aim to explore the proposed mechanisms and pathophysiology for heart failure in patients with a systemic right ventricle in these two subsets of patients.