Identification of acyl-homoserine lactone signal molecules produced by Nitrosomonas europaea strain Schmidt
Identification of acyl-homoserine lactone signal molecules produced by Nitrosomonas europaea strain Schmidt
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DOI：
10.1128/aem.71.8.4906-4909.2005
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发表时间：
2005-08-01
影响因子：
4.4
通讯作者：
Hickey, WJ
中科院分区：
文献类型：
--
作者：
Burton, EO;Read, HW;Hickey, WJ
欧洲亚硝酸单胞菌Schmidt菌株至少产生三种酰基高丝氨酸内酯(AHL)信号分子：C-6-高丝氨酸内酯(HSL)、C-8-HSL和C-10-HSL。用三种独立的方法从恒化器培养流出物的提取物中鉴定了这些化合物。出水中的AHL浓度很低(0.4至2.2 nM)，但在已知的诱导AHL反应系统的范围内。欧洲核糖核酸菌株Schmidt基因组中没有Luxi和LuxM同源物，这表明AHL的合成是通过另一条途径发生的，可能是由HDTS同源物介导的。据我们所知，本报告第一次记录了由欧洲夜蛾产生的AHL的类型和水平。
Nitrosomonas europaea strain Schmidt produces at least three acyl homoserine lactone (AHL) signal molecules: C-6-homoserine lactone (HSL), C-8-HSL, and C-10-HSL. These compounds were identified in extracts of chemostat culture effluent by three independent methods. The concentrations of AHL in effluent were low (0.4 to 2.2 nM) but within the range known to induce AHL-responsive systems. The absence of LuxI and LuxM homologs from the genome of N. europaea strain Schmidt suggested that AHL synthesis occurs by an alternate pathway, possibly mediated by an HdtS homolog. To the best of our knowledge, the present report is the first to document the types and levels of AHLs produced by N. europaea.