Serum Concentrations of Markers of TNFα and Fas-Mediated Pathways and Renal Function in Nonproteinuric Patients with Type 1 Diabetes
Serum Concentrations of Markers of TNFα and Fas-Mediated Pathways and Renal Function in Nonproteinuric Patients with Type 1 Diabetes
复制标题
DOI:
10.2215/cjn.03010608
复制
发表时间:
2009-01-01
影响因子:
9.8
通讯作者:
Krolewski, Andrzej S.
中科院分区:
文献类型:
--
作者:
Niewczas, Monika A.;Ficociello, Linda H.;Krolewski, Andrzej S.
Background and objectives: The aim of our study was to examine serum markers of the TNF and Fas pathways for association with cystatin-C based estimated glomerular filtration rate (cC-GFR) in subjects with type 1 diabetes (T1DM) and no proteinuria.Design, setting, participants, & measurements: The study group (the 2nd Joslin Kidney Study) comprised patients with T1DM and normoalbuminuria (NA) (n = 363) or microalbuminuria (MA) 01 = 304). Impaired renal function (cC-GFR