Bouton ultrastructure and synaptic growth in a frog autonomic ganglion.
Bouton ultrastructure and synaptic growth in a frog autonomic ganglion.
复制标题
青蛙自主神经节的布顿超微结构和突触生长。
DOI：
10.1002/cne.902810113
复制
发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Sargent,PB
中科院分区：
文献类型：
--
作者：
Streichert,LC;Sargent,PB
非洲爪蟾的变态后生长伴随着心脏中自主神经元的大小和与其表面接触的突触终扣数量的增加。为了确定个体终扣的性质是否随着其数量的增加而变化，使用连续切片电子显微镜检查变态末期和成体的终扣超微结构。研究了终扣接触面积、每个终扣的活性区数量、活性区大小、活性区所占终扣面积的百分比以及囊泡密度。没有发现任何参数检查的两个钮人口之间的差异。这些结果支持这一假设，即终扣是突触生长的结构单位，从而增加突触接触的总面积，通过增加终扣，而不改变其形态学特性。
Postmetamorphic growth in the frog,Xenopus laevis, is accompanied by an increase both in the size of autonomic neurons in the heart and in the number of synaptic boutons that contact their surface. To determine whether the properties of individual boutons change as their number increases, serial‐section electron microscopy was used to examine bouton ultrastructure at the end of metamorphosis and in the adult. The area of bouton contact, number of active zones per bouton, active zone size, percent of bouton area occupied by active zone, and vesicle density were examined. No differences were found between the two bouton populations for any of the parameters examined. These results support the hypothesis that boutons are structural units of synaptic growth, whereby the total area of synaptic contact increases through the addition of boutons without a change in their morphological properties.