The kinetics of S-transnitrosation -: A reversible second-order reaction
The kinetics of S-transnitrosation -: A reversible second-order reaction
复制标题
DOI：
10.1006/abio.1999.4199
复制
发表时间：
1999-08-01
影响因子：
2.9
通讯作者：
Hogg, N
中科院分区：
文献类型：
--
作者：
Hogg, N
硫醇和S-亚硝基硫醇之间的转亚硝化作用被认为是信号转导的一种机制。这种反应的动力学很好地符合可逆的二级模型。从这个模型得到的参数给出了正向和反向速率常数和在生理温度和pH值的平衡位置。此外，方法计算的亚硝酰基官能团的平衡分布在混合物中的三个硫醇。(C)北京：科学出版社.
Transnitrosation between thiols and S-nitrosothiols has been suggested to be a mechanism of signal transduction. This kinetics of such reactions fit well to a reversible second-order model. Parameters derived from this model give both the forward and reverse rate constants and the equilibrium position at physiological temperature and pH. In addition, methods are shown for calculating the equilibrium distribution of the nitrosyl function group in mixtures of up to three thiols. (C) 1999 Academic Press.