Isolation and Transplantation Experiments
Isolation and Transplantation Experiments
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分离与移植实验
DOI：
10.1007/978-3-642-65964-5_15
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发表时间：
1975
影响因子：
2.7
通讯作者：
S. Hörstadius
中科院分区：
文献类型：
--
作者：
S. Hörstadius
实验胚胎学的故事开始于研究单个早期卵裂细胞的发育。CHABRY（1887）和ROUX（1888）用针刺死了海鞘卵的卵裂球，并跟踪了它们生活伴侣的行为。ROUX被称为实验胚胎学之父（Entwicklungsmechanik）。几年后，DRIESCH（1891）和FIEDLER（1891）通过振荡分离了海胆卵的2细胞期卵裂球。后来，HERBST发现海水中钙离子的缺乏有利于分离，这放松了卵裂细胞之间的接触（1900）。在世纪之交的几十年里，西奥多·博韦里（Theodor BOVERI）、汉斯·德里斯（Hans DRIESCH）、柯特·赫布斯特（Curt Herbst）、托马斯·亨特·摩根（Hunt MORGAN）等人发表了大量论文，使海胆卵成为发育生理学的重要研究对象之一，并一直保持至今。
The story of experimental embryology begins with attempts to study the development of single early cleavage cells. Blastomeres of ascidian eggs were killed by CHABRY (1887) and ROUX (1888) killed blastomeres of amphibian eggs by pricking them with a needle and the behaviour of their living partners was followed. ROUX has been called the father of experimental embryology (Entwicklungsmechanik). A few years later, DRIESCH (1891) and FIEDLER (1891) isolated blastomeres of 2-cell stages of sea urchin eggs by shaking. Later, it was discovered by HERBST that isolation is facilitated by lack of calcium ions in seawater which loosens the contact between cleavage cells (1900). A flow of papers in the decades at the turn of the century by Theodor BOVERI, Hans DRIESCH, Curt HERBST, Thomas Hunt MORGAN, and others, gave the sea urchin egg a position as one of the foremost objects for developmental physiology, a position held ever since.