The Glasgow Dyspepsia Severity Score - A tool for the global measurement of dyspepsia
The Glasgow Dyspepsia Severity Score - A tool for the global measurement of dyspepsia
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DOI：
10.1097/00042737-199610000-00006
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发表时间：
1996-10-01
影响因子：
2.1
通讯作者：
McColl, KEL
中科院分区：
文献类型：
--
作者：
ElOmar, EM;Banerjee, S;McColl, KEL
目的：目前还没有可靠的工具来提供各种上消化道疾病患者消化不良严重程度的全球测量。我们设计了一份问卷，记录症状出现的频率、对日常活动的影响、休假时间、就医频率、临床调查以及非处方药和处方药的使用情况。本研究的目的是评估问卷的重复性、效度、响应度和操作时间。方法和结果：对于观察者内部变量，一名作者访问了50名受试者(25名男性)，其中包括20名健康志愿者和30名患有各种上消化道疾病的受试者。一周后，同一位作者重复了采访，他对第一次采访的消化不良评分视而不见。第二个作者对诊断和受试者身份视而不见，并对所有问卷进行了评分。消化不良评分第1天为6.78分，第2天为6.80分，第1天和第2天的变异系数为2%。对于观察者间的差异，30名非溃疡性消化不良(NUD)患者由一名作者采访，另一名作者在24小时内在另一单独场合重复采访，第二名作者对第一次采访的得分视而不见。第一作者的平均消化不良评分为10.7分，第二作者为10.9分，两作者之间的变异系数为8%。通过比较健康志愿者和上消化道疾病患者的消化不良评分来评估其有效性。80例健康志愿者平均得分为1.16(0~7分)，其中70例十二指肠溃疡(DU)患者(平均11.1分，6~16分)和80例非十二指肠溃疡(NUD)患者(平均10.5分，6~17分)显著高于正常对照组(P
Objective: There is currently no reliable tool for providing a global measurement of the severity of dyspepsia in patients with a variety of upper gastrointestinal disorders. We have designed a questionnaire which records frequency of symptoms, effect on routine activities, time off work, frequency of medical consultations, clinical investigations and use of over-the-counter and prescribed medications. The objective of the paper was to assess this questionnaire with respect to reproducibility, validity, responsiveness and performance time.Methods and results: For intra-observer variation, one author interviewed 50 subjects (25 males) including 20 healthy volunteers and 30 with a variety of upper gastrointestinal pathologies. The interview was repeated one week later by the same author who was blinded to the dyspepsia score for the first interview. The second author, who was blinded to the diagnoses and subject identity, scored all the questionnaires. The mean dyspepsia score was 6.78 on Day 1 and was similar at 6.80 on Day 2. The coefficient of variation between Days 1 and 2 was 2%. For inter-observer variation, 30 patients with non-ulcer dyspepsia (NUD) were interviewed by one author and the interview was repeated on a separate occasion within 24 h by a second author who was blinded to the score from the first interview. The mean dyspepsia score for the first author was 10.7 and for the second author 10.9 with a coefficient of variation between the two authors of 8%. Validity was assessed by comparing the dyspepsia scores in healthy volunteers and patients with upper gastrointestinal diseases. The mean score in 80 healthy volunteers was 1.16 (range: 0-7) and was significantly higher in 70 duodenal ulcer (DU) patients (mean score 11.1, range: 6-16) and 80 NUD patients (mean score 10.5, range: 6-17) (P