Continuous Flow Peritoneal Dialysis
Continuous Flow Peritoneal Dialysis
复制标题
连续流腹膜透析
DOI：
10.1177/089686080102103s23
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发表时间：
2001
影响因子：
2.8
通讯作者：
R. Dell'aquila
中科院分区：
文献类型：
--
作者：
C. Ronco;R. Dell'aquila
Gotch（32）显然，这些治疗方案达到了标准Kt/V值，这是目前治疗可达到的最高值。事实上，使用CFPD，可以探索透析液流速和血液流速都不是限制因素的清除区域。该区域中的间隙值近似于单位面积的传质系数（MTAC）的值。显然，CAPD的相对效率可以通过增加交换的体积和交换的次数来提高。APD也是如此。间歇性PD（每周三次）在大多数情况下产生不足的清除，尽管所有的努力。CFPD可以达到更高的效率水平，但该技术假设每次使用大量的流体-高达100 L，如示例所示。在这一点上，成本和技术问题成为评估技术的重要因素。CFPD中涉及的高透析液流量需要大量液体。PD溶液在高流量条件下的生物相容性和耐受性是一个问题。必须有足够的腹膜通路。其他关注的问题是
by Gotch (32). Clearly, these treatment schedules reach standard Kt/V values that are among the highest achievable with current therapies. In fact, with CFPD, exploration of the region of clearance in which neither dialysate flow rate nor blood flow rate are limiting factors becomes possible. Clearance values in that region approximate the value of the mass transfer coefficient (MTAC) per area. Clearly, the relative efficiency of CAPD can be improved by increasing the volume exchanged and the number of exchanges. The same is true for APD. Intermittent PD (three times weekly) in most cases produces inadequate clearances, despite all efforts. Higher levels of efficiency can be reached with CFPD, but that technique assumes the use of huge amounts of fluid per session—up to 100 L as shown in the example. At this point, the cost and the technological issues become important in evaluating the technique. The high dialysate flows involved in CFPD are what require the large amounts of fluid. The biocompatibility and tolerability of the PD solution under high-flow conditions is an issue. Adequate peritoneal access must be available. Other concerns are the