One-laser interferometric broadband coherent anti-Stokes Raman scattering
One-laser interferometric broadband coherent anti-Stokes Raman scattering
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DOI：
10.1364/oe.14.003631
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发表时间：
2006-04-17
期刊：
影响因子：
3.8
通讯作者：
Cicerone, MT
中科院分区：
文献类型：
--
作者：
Kee, TW;Zhao, HX;Cicerone, MT
介绍了一种用于消除宽带相干反斯托克斯拉曼散射(CARS)显微镜中非共振背景的干涉技术。CARS显微镜已经被用于对一些生物样品和过程进行成像，但这些研究大多局限于通过探测C-H拉伸来检测生物系统中的脂质。非共振背景和非相干噪声源可以很容易地淹没来自其他分子振动的不太强烈的信号。在这项研究中，我们展示了一种单激光宽带干涉技术，该技术将CARS信号中与自发拉曼散射相关的分量从非共振背景中分离出来，并以液体苯腈为模型系统。
We introduce an interferometric technique for eliminating the non-resonant background of broadband coherent anti-Stokes Raman scattering (CARS) microscopy. CARS microscopy has been used for imaging a number of biological samples and processes, but the studies are mostly limited to detecting lipids in biological systems by probing the C-H stretch. Non-resonant background and incoherent noise sources can easily overwhelm less intense signals from other molecular vibrations. In this study, we demonstrate a one-laser broadband interferometric technique that separates the spontaneous Raman scattering-related component of the CARS signal from the non-resonant background using liquid benzonitrile as a model system.