Anisotropic Compressive Properties of Passive Porcine Muscle Tissue
Anisotropic Compressive Properties of Passive Porcine Muscle Tissue
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DOI：
10.1115/1.4028088
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发表时间：
2014-11-01
影响因子：
1.7
通讯作者：
Williams, Lakiesha N.
中科院分区：
文献类型：
--
作者：
Pietsch, Renee;Wheatley, Benjamin B.;Williams, Lakiesha N.
人体大约有434块肌肉，占身体重量的40-50%。肌肉在本质上是分层的，并且被组织成包裹在结缔组织中的逐渐变大的单元。与许多软组织一样，肌肉具有非线性粘弹性行为，但肌肉也具有独特的兴奋性和收缩性。肌肉的机械测试已经针对碰撞模型、压疮模型、背痛和其他疾病模型进行。大多数以前的肌肉生物力学研究已经与纵向拉伸性能，因为这是肌肉在正常生理条件下的主要操作模式。损伤条件，特别是高频率损伤，可以使肌肉暴露于多种应力状态。压缩应力可导致组织损伤，这可能是不可逆的。在这项研究中，我们评估了猪肌肉组织在0.1 s（-1），0.01 s（-1）或0.001 s（-1）的横向和纵向压缩下的结构-性能关系。我们的研究结果表明，最初的脚趾区域，其次是增加应力的肌肉在纵向和横向方向测试到50%的应变。还观察到应变率依赖性，其中较高的应变率在50%应变下显示出显著更多的应力。横向方向的肌肉比纵向方向的肌肉明显更硬，表明各向异性。纤维在纵向的平均面积显示出增加的平均纤维面积和减少的平均纤维面积在横向方向。这项研究中获得的数据可以帮助了解肌肉损伤是如何引起的，从低能量应变到高速率爆炸事件，也可以用于开发计算损伤模型。
The body has approximately 434 muscles, which makes up 40-50% of the body by weight. Muscle is hierarchical in nature and organized in progressively larger units encased in connective tissue. Like many soft tissues, muscle has nonlinear visco-elastic behavior, but muscle also has unique characteristics of excitability and contractibility. Mechanical testing of muscle has been done for crash models, pressure sore models, back pain, and other disease models. The majority of previous biomechanical studies on muscle have been associated with tensile properties in the longitudinal direction as this is muscle's primary mode of operation under normal physiological conditions. Injury conditions, particularly high rate injuries, can expose muscle to multiple stress states. Compressive stresses can lead to tissue damage, which may not be reversible. In this study, we evaluate the structure-property relationships of porcine muscle tissue under compression, in both the transverse and longitudinal orientations at 0.1 s(-1), 0.01 s(-1), or 0.001 s(-1). Our results show an initial toe region followed by an increase in stress for muscle in both the longitudinal and transverse directions tested to 50% strain. Strain rate dependency was also observed with the higher strain rates showing significantly more stress at 50% strain. Muscle in the transverse orientation was significantly stiffer than in the longitudinal orientation indicating anisotropy. The mean area of fibers in the longitudinal orientation shows an increasing mean fiber area and a decreasing mean fiber area in the transverse orientation. Data obtained in this study can help provide insight on how muscle injuries are caused, ranging from low energy strains to high rate blast events, and can also be used in developing computational injury models.