TOTAL SYNTHESES OF PHLEICHROME, CALPHOSTIN-A, AND CALPHOSTIN-D - UNUSUAL STEREOSELECTIVE AND STEREOSPECIFIC REACTIONS IN THE SYNTHESIS OF PERYLENEQUINONES
TOTAL SYNTHESES OF PHLEICHROME, CALPHOSTIN-A, AND CALPHOSTIN-D - UNUSUAL STEREOSELECTIVE AND STEREOSPECIFIC REACTIONS IN THE SYNTHESIS OF PERYLENEQUINONES
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DOI：
10.1016/s0040-4039(00)92105-1
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发表时间：
1991-02-11
影响因子：
1.8
通讯作者：
BROKA, CA
中科院分区：
文献类型：
--
作者：
BROKA, CA
本文报道了三种蛋白激酶C抑制剂？。 目前的路线提供了对映体纯形式的目标，并代表了第一个成功的方法，这类生物学上重要的代谢物。
This report describes the total synthesis of phleichrome, calphostin A and calphostin D - three protein kinase C inhibitory perylenequinones. The present route affords the targets in enantiomerically pure form and represents the first successful approach to this biologically important class of metabolites.