Balance control in peripheral neuropathy: Are patients equally unstable under static and dynamic conditions?
Balance control in peripheral neuropathy: Are patients equally unstable under static and dynamic conditions?
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DOI：
10.1016/j.gaitpost.2005.04.002
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发表时间：
2006-04-01
期刊：
影响因子：
2.4
通讯作者：
Schieppati, M
中科院分区：
文献类型：
--
作者：
Nardone, A;Grasso, M;Schieppati, M
本研究的目的是评估在静态和动态条件下，神经病变患者本体感觉输入受损对平衡控制的潜在不同影响。我们招募了20名正常受试者和27名患有不同程度影响大、中传入纤维的神经病的患者。其中5例为1A型（CMT1A）， 8例为CMT2型（CMT2）， 14例为糖尿病多发性神经病（Diabetics）。在稳定测量平台上测量安静站立时的平衡表明，CMT2和糖尿病患者的摇摆面积（SA）比正常受试者或CMT1A受试者大，无论是睁眼还是闭眼。CMT2和糖尿病患者的II组传入纤维的估计传导速度（CV）低于正常受试者和CMT1A。在所有患者中，SA随着H组CV减慢而增加。在动态平衡任务中，患者组的头部a - p位移与正常人相比仅略有增加，尽管头部随脚位移的延迟增加。所有患者组在动态状态下的表现都是不可预测的，这与他们在安静姿势时的不平衡是不同的，这可能表明这些患者学会了利用预期姿势策略。(c) 2005 Elsevier B.V.版权所有
The aim of this investigation was to assess the potentially different effects of impaired proprioceptive input in balance control under static and dynamic conditions in neuropathic patients. We recruited 20 normal subjects and 27 patients affected by neuropathies known to affect to a different extent large and medium size afferent fibres. The patients comprised 5 with Charcot-Marie-Tooth disease type 1A (CMT1A), 8 with CMT type 2 (CMT2) and 14 with Diabetes polyneuropathy (Diabetics). Measurement of balance during quiet stance on a stabilometric platform showed that sway area (SA) was larger in the CMT2 and Diabetics than normal subjects or in CMT1A, under both eyes open and closed conditions. The estimated conduction velocity (CV) of the group II afferent fibres was lower in CMT2 and Diabetics than in normal subjects and CMT1A. Across all patients, SA increased as a function of the slowing of group H CV. During a dynamic balance task the head A-P displacement was only slightly increased in the patient groups with respect to normals, despite the increased delay at which the head followed displacement of the feet. The unpredictably good performance of all patient groups under dynamic condition, which was at variance with their imbalance during quiet stance, may indicate that these patients learnt to exploit anticipatory postural strategies. (c) 2005 Elsevier B.V. All rights reserved.