PHORBOL ESTER ENHANCES DEOXYNUCLEOSIDE INCORPORATION WHILE INHIBITING PROLIFERATION OF K-562 CELLS
PHORBOL ESTER ENHANCES DEOXYNUCLEOSIDE INCORPORATION WHILE INHIBITING PROLIFERATION OF K-562 CELLS
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DOI：
10.1002/cyto.990060614
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发表时间：
1985-01-01
期刊：
影响因子：
--
通讯作者：
NECKERS, LM
中科院分区：
文献类型：
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作者：
COLAMONICI, OR;TREPEL, JB;NECKERS, LM
最近发展了一种新的技术来研究溴脱氧尿苷掺入DNA作为细胞周期时相分布的函数。我们已经观察到，造血细胞系K-562的处理导致细胞生长的完全和立即停止，尽管氚化胸苷掺入显著升高长达5天。我们已经利用新描述的技术来研究这种现象。
Recently a new technique has been developed to study bromodeoxyuridine incorporation into DNA as a function of the cell cycle phase distribution. We have made the observation that treatment of the hematopoietic cell line K-562 results in a complete and immediate cessation of cell growth, although tritiated thymidine incorporation is markedly elevated for as long as 5 days. We have made use of that newly described technique to study this phenomenon.