MOUSE CYTOMEGALOVIRUS INFECTION. II. OBSERVATIONS DURING PROLONGED INFECTIONS.
MOUSE CYTOMEGALOVIRUS INFECTION. II. OBSERVATIONS DURING PROLONGED INFECTIONS.
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小鼠巨细胞病毒感染。
DOI：
10.1093/oxfordjournals.aje.a120450
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发表时间：
1964
影响因子：
--
通讯作者：
D. Medearis
中科院分区：
文献类型：
--
作者：
D. Medearis
巨细胞病毒（CMV）感染的特点是显著的慢性：病毒可从明显无症状的儿童的咽拭子和尿液标本中恢复，时间为15至24个月(1)；在一些新生儿巨细胞包涵性疾病（CID）存活的儿童中，病毒尿持续3年或更长时间（2,3）；在小鼠中，有报道称腹腔注射小鼠巨细胞病毒（小鼠唾液腺病毒（MCMV））后持续1年的慢性亚临床感染(4)。
Cytomegalovirus (CMV) infections are characterized by a remarkable chronicity: virus was recovered from throat swab and urine specimens obtained from apparently asymptomatic children for periods extending from 15 to 24 months (1); in some of the children who survived neonatal cytomegalic inclusion disease (CID) viruria persisted for 3 years or more (2, 3); and in mice, chronic subclinical infections lasting 1 year after the intraperitoneal inoculation of mouse CMV (mouse salivary gland virus (MCMV)) have been reported (4).