Paracentesis-Induced Circulatory Dysfunction With Modest-Volume Paracentesis Is Partly Ameliorated by Albumin Infusion in Acute-on-Chronic Liver Failure
Paracentesis-Induced Circulatory Dysfunction With Modest-Volume Paracentesis Is Partly Ameliorated by Albumin Infusion in Acute-on-Chronic Liver Failure
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DOI：
10.1002/hep.31071
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发表时间：
2020-07-09
期刊：
影响因子：
13.5
通讯作者：
Sarin, Shiv Kumar
中科院分区：
文献类型：
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作者：
Arora, Vinod;Vijayaraghavan, Rajan;Sarin, Shiv Kumar
背景和目的穿刺术引起的循环功能障碍（PICD）是肝硬化患者大容量（>5 L）穿刺术的严重并发症，输注白蛋白可减少PICD。目前缺乏关于慢性加急性肝功能衰竭（ACLF）中PICD的数据。由于ACLF患者比失代偿期肝硬化患者有更大的血流动力学紊乱，我们研究了中等容量穿刺术（MVP）是否会发生PICD以及白蛋白输注的作用。方法和结果共80例ACLF患者接受了
Background and Aims Paracentesis-induced circulatory dysfunction (PICD) is a serious complication of large-volume (>5 L) paracentesis in cirrhosis and is reduced with albumin infusion. There is a lack of data on PICD in acute-on-chronic liver failure (ACLF). Because ACLF patients have greater hemodynamic derangements than patients with decompensated cirrhosis, we investigated whether PICD could develop with modest-volume paracentesis (MVP) and the role of albumin infusion. Approach and Results A total of 80 ACLF patients undergoing