Design guidelines for optical resonator biochemical sensors
Design guidelines for optical resonator biochemical sensors
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DOI：
10.1364/josab.26.001032
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发表时间：
2009-05-01
影响因子：
1.9
通讯作者：
Kimerling, Lionel C.
中科院分区：
文献类型：
--
作者：
Hu, Juejun;Sun, Xiaochen;Kimerling, Lionel C.
我们提出了一种基于介电光学谐振器的生化折射传感器的设计工具。类似于广泛接受的光电探测器的品质因数，探测率D*，我们引入了一个新的传感器系统的品质因数，时间归一化的灵敏度S*，允许定量，跨技术平台的谐振器传感器与独特的设备设计和询问配置之间的比较。的功能依赖性的S* 的设备参数，如谐振腔的品质因数（Q），消光比，系统噪声，和光源光谱带宽，通过使用洛伦兹峰拟合算法和蒙特卡罗模拟进行评估，以提供理论见解和有用的设计指南光学谐振腔传感器。重要的是，我们发现，S* 严重依赖于腔Q因子，我们开发了一种方法，优化传感器的分辨率和灵敏度作为腔Q因子的函数噪声。最后，我们比较传感器波长分辨率的模拟预测与实验结果在Ge 17 Sb 12 S71谐振器，并确认良好的协议。(C)2009年美国光学学会
We propose a design tool for dielectric optical resonator-based biochemical refractometry sensors. Analogous to the widely accepted photodetector figure of merit, the detectivity D*, we introduce a new sensor system figure of merit, the time-normalized sensitivity S*, to permit quantitative, cross-technology-platform comparison between resonator sensors with distinctive device designs and interrogation configurations. The functional dependence of S* on device parameters, such as resonant cavity quality factor (Q), extinction ratio, system noise, and light source spectral bandwidth, is evaluated by using a Lorentzian peak fitting algorithm and Monte Carlo simulations to provide theoretical insights and useful design guidelines for optical resonator sensors. Importantly, we find that S* critically depends on the cavity Q factor, and we develop a method of optimizing sensor resolution and sensitivity to noise as a function of cavity Q factor. Finally, we compare the simulation predictions of sensor wavelength resolution with experimental results obtained in Ge17Sb12S71 resonators, and good agreement is confirmed. (C) 2009 Optical Society of America