Histochemical and immunohistochemical studies on the articular disk of the temporomandibular joint in rats.
Histochemical and immunohistochemical studies on the articular disk of the temporomandibular joint in rats.
复制标题
大鼠颞下颌关节关节盘的组织化学和免疫组织化学研究。
DOI：
10.1159/000146729
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Kazumasa Hoshino
中科院分区：
文献类型：
--
作者：
Shigeyuki Fujita;Kazumasa Hoshino
用组织化学和免疫组织化学方法研究了手术诱导的错(牙合)畸形对成年雄性大鼠关节盘的影响。手术组大鼠关节盘中段胶原纤维和软骨细胞数量明显少于对照组，胶原纤维变得更加波浪状、粗糙和不规则。部分实验大鼠可见成簇的软骨细胞。本实验表明，手术诱导的错(牙合)畸形可引起颞下颌关节盘细胞外基质中胶原纤维和软骨细胞的明显变化。
The effects of surgically induced malocclusion upon the articular disk of the temporomandibular joint in adult male rats were investigated histochemically and immunohistochemically using antibody against type II collagen. In the intermediate portion of the articular disk, the number of collagen fibers and chondrocytes was much less and the collagen fibers became more wavy, rough and irregular in surgically operated rats than in control rats. Clusters of chondrocytes were found in some experimental rats. The present experiments revealed that surgically induced malocclusion causes noticeable changes in collagen fibers and chondrocytes within the extracellular matrix of the articular disk of the temporomandibular joint.