Responses of neurons in primary visual cortex are modulated by eye position.
Responses of neurons in primary visual cortex are modulated by eye position.
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DOI：
10.1152/jn.1993.69.6.2258
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发表时间：
1993-06
影响因子：
2.5
通讯作者：
T. Weyand;Malpeli Jg
中科院分区：
文献类型：
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作者：
T. Weyand;Malpeli Jg
1. 我们测试了眼位对在动眼肌任务中训练的醒猫初级视觉皮层中88个神经元视觉兴奋性的影响。对于大多数细胞，我们检查了在中心凝视，中心左侧8度和中心右侧8度时，视网膜相同的刺激所引起的反应。2. 观察到眼睛位置对40%的细胞有影响。对于13%，响应度变化了2倍或更多。最常见的是，注视一侧时反应最大，注视另一侧时反应最小，注视中心时反应居中。只有四个细胞例外，它们的兴奋性随着注视中心两侧而对称变化。3. 与眼位相关的兴奋性变异性是一种广泛存在的现象，已在外侧膝状核、V1和纹状外皮层中观察到。这些结果与这样一种信念是一致的，即这种可变性被用于从视网膜移植输入构建以头部为中心的参考框架。
1. We tested the effects of eye position on the visual excitability of 88 neurons in the primary visual cortex of awake cats trained in oculomotor tasks. For most cells, we examined responses evoked by retinotopically identical stimuli for centered gaze, 8 degrees to the left of center, and 8 degrees to the right of center. 2. An effect of eye position was observed for 40% of the cells. For 13%, responsiveness varied by a factor of 2 or more. Most commonly, response was maximal with gaze shifted to one side, minimal when shifted to the opposite side, and intermediate for centered fixation. The exceptions were four cells for which excitability varied symmetrically with fixations to either side of center. 3. Variability in excitability associated with eye position is a wide-spread phenomenon, having been observed in the lateral geniculate nucleus, V1, and extrastriate cortex. These results are consistent with the belief that such variability is utilized in constructing a head-centered frame of reference from a retinotopic input.