Socio-emotional and adaptive behaviour in children treated for severe anaemia at Lira Regional Referral Hospital, Uganda: a prospective cohort study.
Socio-emotional and adaptive behaviour in children treated for severe anaemia at Lira Regional Referral Hospital, Uganda: a prospective cohort study.
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DOI：
10.1186/s13034-020-00352-4
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发表时间：
2020-11-26
影响因子：
5.6
通讯作者：
Bangirana P
中科院分区：
文献类型：
--
作者：
Ssemata AS;Opoka RO;Ssenkusu JM;Nakasujja N;John CC;Bangirana P
严重贫血是一项全球公共卫生挑战，通常与撒哈拉以南非洲 5 岁以下儿童的发病率和死亡率相关。然而，对于资源匮乏环境中 5 岁以下患有严重贫血的儿童的行为表现知之甚少。我们调查了乌干达北部被诊断患有严重贫血的 5 岁以下儿童的社会情感和适应行为。我们对在乌干达利拉地区转诊医院接受严重贫血治疗的 6-42 个月儿童 (n = 171) 进行了一项基于医院的前瞻性队列研究。出院后 14 天，使用贝利婴幼儿发育量表（第三版）评估社会情感和适应行为。每个领域的年龄调整 z 分数是使用来自相同环境的每个年龄类别的健康社区儿童 (n = 88) 的分数计算的。在对所有量表的年龄体重 z 得分、社会经济地位、母亲教育程度、父亲教育程度和父亲就业情况进行调整后，采用多元线性回归比较两组之间的社会情感和适应性行为量表的 z 得分。与健康社区对照相比，严重贫血儿童的[调整平均分（标准误）]、社会情绪[− 0.29, (0.05) vs. 0.01, (0.08), P = 0.002]较差；但不是整体/复合适应性行为[− 0.10, (0.05) vs. - 0.01, (0.07), P = 0.343]。在适应性行为分量表中，患有SA的儿童在社区使用方面的得分明显较差[调整后的平均得分（标准误差）]，[− 0.63, (0.10) vs. - 0.01, (0.13), P < 0.001]；和休闲 [− 0.35, (0.07) vs. − 0.02, (0.07), P = 0.036] 技能。这项研究表明，乌干达北部 5 岁以下儿童的严重贫血与临床恢复后短期社会情绪评分较差有关。我们建议进行长期随访，以确定这些问题的进程，并采取适当的干预措施，以减轻乌干达患有严重贫血的 5 岁以下儿童的行为负担。
Severe anaemia is a global public health challenge commonly associated with morbidity and mortality among children < 5 years of age in Sub-Saharan Africa. However, less is known about the behavioural performance of children < 5 years surviving severe anaemia in low resource settings. We investigated social-emotional and adaptive behaviour in children < 5 years diagnosed with severe anaemia in Northern Uganda. We conducted a hospital based prospective cohort study among children 6—42 months who were treated for severe anaemia (n = 171) at Lira Regional Referral Hospital, Uganda. Socio-emotional and adaptive behaviour were assessed 14 days post discharge using the Bayley Scales of Infant and Toddler Development, 3rd edition. Age-adjusted z-scores for each domain were calculated using scores from healthy community children (n = 88) from the same environment for each age category. Multiple linear regression was used to compare z-scores in the social-emotional and adaptive behaviour scales between the two groups after adjusting for weight-for-age z-score, social economic status, mother’s education, father’s education and father’s employment on all the scales. Compared with healthy community controls, children with severe anaemia had poorer [adjusted mean scores (standard error)], socio-emotional [− 0.29, (0.05) vs. 0.01, (0.08), P = 0.002]; but not overall/ composite adaptive behaviour [− 0.10, (0.05) vs. − 0.01, (0.07), P = 0.343]. Within the adaptive behaviour subscales, children with SA displayed significantly poorer scores on the community use [adjusted mean score (standard error)], [− 0.63, (0.10) vs. − 0.01, (0.13), P < 0.001]; and leisure [− 0.35, (0.07) vs. − 0.02, (0.07), P = 0.036] skills. This study suggests that severe anaemia in children < 5 years is associated with poor social-emotional scores in the short-term post clinical recovery in Northern Uganda. We recommend long-term follow-up to determine the course of these problems and appropriate interventions to reduce the behavioural burden among children < 5 years surviving severe anaemia in Uganda.
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DOI：
10.1073/pnas.0709715105
发表时间：
2008-02-19
影响因子：
11.1
作者：
Casals-Pascual, Climent;Idro, Richard;Newton, Charles R. J. C.
通讯作者：
Newton, Charles R. J. C.
影响因子：
3.7
作者：
Bangirana, Paul;John, Chandy C.;Boivin, Michael J.
通讯作者：
Boivin, Michael J.
DOI：
10.1016/b978-0-12-374177-6.10005-4
发表时间：
2010-01-01
期刊：
BAYLEY-III CLINICAL USE AND INTERPRETATION
影响因子：
--
作者：
Breinbauer, Cecilia;Mancil, Twyla L.;Greenspan, Stanley
通讯作者：
Greenspan, Stanley
DOI：
10.1097/00001503-200410000-00003
发表时间：
2004-10-01
期刊：
Current opinion in anaesthesiology
影响因子：
--
作者：
Hare, Gregory M T
通讯作者：
Hare, Gregory M T
影响因子：
11.8
作者：
Bangirana, Paul;Opoka, Robert O.;John, Chandy C.
通讯作者：
John, Chandy C.