"I had Made the Decision, and No One was Going to Stop Me" -Facilitators of PrEP Adherence During Pregnancy and Postpartum in Cape Town, South Africa.
"I had Made the Decision, and No One was Going to Stop Me" -Facilitators of PrEP Adherence During Pregnancy and Postpartum in Cape Town, South Africa.
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DOI：
10.1007/s10461-021-03320-x
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发表时间：
2021-12
影响因子：
4.4
通讯作者：
Myer L
中科院分区：
文献类型：
--
作者：
Joseph Davey DL;Knight L;Markt-Maloney J;Tsawe N;Gomba Y;Mashele N;Dovel K;Gorbach P;Bekker LG;Coates TJ;Myer L
PrEP是安全有效的，但需要在潜在的艾滋病毒暴露期间坚持使用，然而促进产妇长期坚持使用的因素尚不清楚。我们对25名产后妇女进行了半结构化访谈，这些妇女在孕妇和产后妇女的PrEP服务中报告了高依从性（在过去30天内使用PrEP≥25天，并且在怀孕/产后期间从未错过PrEP处方）。主题方法指导了编码和分析的迭代过程。被确定为最佳PrEP使用驱动因素的主题是艾滋病毒风险认知，主要是因为伴侣的行为和未知的血清状态，以及强烈希望有一个没有艾滋病毒的婴儿。报告披露PrEP使用情况促进了PrEP依从性。女性讨论了伴侣和家人的支持，包括提醒她们每天服用PrEP。主要障碍是预期或经历的耻辱，通过对伴侣和家人进行PrEP教育来克服。孕妇经历了短暂的副作用，但找到了继续服用PrEP的方法，包括在夜间服用PrEP。针对孕妇和产后妇女的预防计划应整合策略，以帮助妇女进行现实的风险评估，并教授披露和获得重要他人支持的技能。
PrEP is safe and effective but requires adherence during potential HIV exposure, yet the facilitators of long-term maternal adherence are not well understood. We conducted semi-structured interviews with 25 postpartum women who reported high adherence (PrEP use ≥ 25 days in last 30-days and never missed a PrEP prescription in pregnancy/postpartum period) within a PrEP service for pregnant and postpartum women. A thematic approach guided an iterative process of coding and analysis. Themes identified as drivers of optimal PrEP use were HIV risk perception, mainly because of partner’s behaviors and unknown serostatus, and a strong desire to have a baby free of HIV. Reported disclosure of PrEP use facilitated PrEP adherence. Women discussed having partner and family support, which included reminders to take PrEP daily. Primary barriers were anticipated or experienced stigma, overcome through education of partners and family about PrEP. Pregnant women experienced transient side-effects, but found ways to continue, including taking PrEP at night. PrEP programs for pregnant and postpartum women should integrate strategies to assist women with realistic appraisals of risk and teach skills for disclosure and securing support from significant others.
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影响因子：
15.8
作者：
Masters SH;Agot K;Obonyo B;Napierala Mavedzenge S;Maman S;Thirumurthy H
通讯作者：
Thirumurthy H
影响因子：
1.7
作者：
McGrath, C. J.;Singa, B.;John-Stewart, G. C.
通讯作者：
John-Stewart, G. C.
影响因子：
1.7
作者：
Joseph Davey DL;Daniels J;Beard C;Mashele N;Bekker LG;Dovel K;Ncayiyana J;Coates TJ;Myer L
通讯作者：
Myer L
DOI：
10.1097/qad.0000000000001922
发表时间：
2018-08-24
期刊：
AIDS (London, England)
影响因子：
--
作者：
Pyra M;Anderson PL;Hendrix CW;Heffron R;Mugwanya K;Haberer JE;Thomas KK;Celum C;Donnell D;Marzinke MA;Bukusi EA;Mugo NR;Asiimwe S;Katabira E;Baeten JM;Partners Demonstration Study Team
通讯作者：
Partners Demonstration Study Team
影响因子：
3.8
作者：
Davey, Dvora L. Joseph;Bekker, Linda-Gail;Johnson, Leigh F.
通讯作者：
Johnson, Leigh F.