The acceptability of self-collected samples for HPV testing vs. the pap test as alternatives in cervical cancer screening
The acceptability of self-collected samples for HPV testing vs. the pap test as alternatives in cervical cancer screening
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DOI：
10.1089/152460902753668466
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发表时间：
2002-04-01
期刊：
影响因子：
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通讯作者：
Salmerón, J
中科院分区：
文献类型：
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作者：
Dzuba, IG;Díaz, EY;Salmerón, J
目的：探讨的可接受性的自我收集的样本进行人乳头瘤病毒（HPV）检测的比较与巴氏test.Methods：研究人群包括1069名妇女20岁及以上的人有资格通过墨西哥社会保障研究所（IMSS）的覆盖范围。这些妇女是在一项更大规模的研究中从参与者中随机选择的，以评估HPV检测作为宫颈癌筛查替代方法的使用。所有参与者都根据明确的指示提供了自我收集的阴道样本进行HPV检测，并进行了巴氏试验。之后，对每一位妇女进行了访谈，了解她对这两种程序的经历和看法。可接受性是衡量的基础上的不适，疼痛，尴尬，隐私，个人治疗的感知在巴氏试验，并了解如何执行的自我采样method.Results：百分之九十三的妇女经历了足够的隐私与巴氏试验，而98%的妇女报告说，隐私与自我采样程序是可以接受的。巴氏试验总是比自我取样引起更多的不适，疼痛和尴尬。68%的女性选择了自我采样。对这种方法的偏好与家庭月收入呈正相关。妇女报告说，自我采样的偏好，因为它是更舒适（71.2%），并导致较少的尴尬（55.8%）。结论：自我采样是更容易接受的巴氏试验，可以提高覆盖率的早期检测计划。结合自我收集的样本来检测HPV可以鼓励那些因必要的盆腔检查而拒绝接受巴氏试验的妇女参与筛查计划。
Objective: To explore the acceptability of the self-collection of samples for human papillomavirus (HPV) testing in comparison with that of the Pap test.Methods: The study population consisted of 1069 women 20 years and older who were eligible for coverage through the Mexican Institute of Social Security (IMSS). These women were randomly selected among participants in a larger study to evaluate the use of HPV testing as an alternative in cervical cancer screening. All participants provided a self-collected vaginal sample for HPV testing according to explicit instructions and underwent a Pap test. Afterwards, each woman was interviewed about her experience and opinion regarding the two procedures. Acceptability was measured by a calculated score based on discomfort, pain, embarrassment, privacy, perception of personal treatment during the Pap test, and understanding of how to perform the self-sampling method.Results: Ninety-three percent of women experienced sufficient privacy with the Pap test, whereas 98% of women reported that privacy with the self-sampling procedure was acceptable. The Pap test consistently provoked more discomfort, pain, and embarrassment than self-sampling. Sixty-eight percent of the women who indicated a test preference chose self-sampling. Preference for this method was positively associated with monthly household income. Women reported a preference for self-sampling because it is more comfortable (71.2%) and causes less embarrassment (55.8%).Conclusions: Self-sampling is more acceptable than the Pap test and could improve coverage rates of early detection programs. The incorporation of self-collected samples to detect HPV could encourage participation in screening programs among those women who reject the Pap test because of the necessary pelvic examination.