Posttreatment High-Grade Glioma: Usefulness of Peak Height Position with Semiquantitative MR Perfusion Histogram Analysis in an Entire Contrast-enhanced Lesion for Predicting Volume Fraction of Recurrence
Posttreatment High-Grade Glioma: Usefulness of Peak Height Position with Semiquantitative MR Perfusion Histogram Analysis in an Entire Contrast-enhanced Lesion for Predicting Volume Fraction of Recurrence
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DOI：
10.1148/radiol.10091461
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发表时间：
2010-09-01
期刊：
影响因子：
19.7
通讯作者：
Kim, Sun Yong
中科院分区：
文献类型：
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作者：
Kim, Ho Sung;Kim, Jang-Hee;Kim, Sun Yong
目的：确定半定量直方图分析整个造影剂增强病变的标准化脑血容量（CBV）是否可以用于预测治疗后高级别胶质瘤复发的体积分数与治疗后变化的比较。材料和方法：机构审查委员会批准了这项回顾性研究。获得知情同意。病理证实肿瘤复发为主组（肿瘤复发组，肿瘤分数>= 50% [n = 14]）、肿瘤及治疗后改变混合组（混合组，肿瘤分数>= 20%和50% [n = 10]）、治疗后改变为主组（治疗改变组，肿瘤分数）39例
Purpose: To determine whether semiquantitative histogram analysis of the normalized cerebral blood volume (CBV) for an entire contrast material-enhanced lesion could be used to predict the volume fraction of posttreatment high-grade glioma recurrence compared with posttreatment change.Materials and Methods: The institutional review board approved this retrospective study. Informed consent was obtained. Thirty-nine patients with pathologically proved predominant tumor recurrence (tumor recurrence group, tumor fraction >= 50% [n = 14]), mixed tumor and posttreatment change (mixed group, tumor fraction >= 20% and, 50% [n = 10]), and predominant posttreatment change (treatment change group, tumor fraction