Changes in gene and genotype frequencies during the development of the grass carp Ctenopharyngodon idella
Changes in gene and genotype frequencies during the development of the grass carp Ctenopharyngodon idella
复制标题
草鱼发育过程中基因和基因型频率的变化
DOI：
10.1111/jfb.13828
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发表时间：
2018
影响因子：
2
通讯作者：
Yaping Wang
中科院分区：
文献类型：
--
作者：
Libo He;Lv Xiong;Aidi Zhang;Yongming Li;Rong Huang;Lanjie Liao;Zuoyan Zhu;Yaping Wang
本研究构建了草鱼的全同胞群体，其群体温度约为500 ℃。在四个早期发育阶段（孵化、第一次摄食、幼鱼和幼鱼）对idella个体进行取样。构建了四个DNA池，并进行了下一代测序。在单核苷酸多态性（SNP）鉴定的基础上，研究了不同发育阶段的基因频率和基因型频率变化。idellawere揭示，这表明在早期发育阶段的死亡不是一个随机的过程。这些发现将为进一步研究确定作为分子育种目标标记的上级等位基因或基因型奠定基础。
In this study, a full‐sib population ofCtenopharyngodon idellawas constructed and approximately 500C. idellaindividuals were sampled at four early developmental stages (hatching, first feeding, juvenile fish and young fish). Four DNA pools were constructed and subjected to next‐generation sequencing. On the basis of the identification of single nucleotide polymorphisms (SNP), changes in gene and genotype frequencies during the developmental progress ofC. idellawere revealed, which indicates that death during the early developmental stage is not a random process. These findings will establish the basis for further studies performed for identifying superior alleles or genotypes as target markers for molecular breeding.