Hepatocellular carcinoma
Hepatocellular carcinoma
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DOI：
10.1016/s0140-6736(98)09148-x
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发表时间：
1999-04-10
期刊：
影响因子：
168.9
通讯作者：
Sorrell, MF
中科院分区：
文献类型：
--
作者：
Schafer, DF;Sorrell, MF
肝细胞癌（HCC）是慢性炎症和纤维化肝病的晚期并发症。除了少数例外，治疗主要是姑息性的，长期生存是罕见的。然而，全球范围内HCC的主要原因是已知的和可预防的。B型和C型肝炎只存在于人类中;这些病毒没有已知的非人类宿主。通过接种预防B型肝炎病毒感染的疫苗和改进治疗丙型肝炎的医疗技术可以阻断病毒的传播;目前还没有开发出针对丙型肝炎的疫苗。
Hepatocellular carcinoma (HCC) for most patients is a terminal complication of chronic inflammatory and fibrotic liver disease. With regrettably few exceptions, treatment is largely palliative, and long-term survival Is rare. However, the major causes of HCC worldwide are known and preventable. Hepatitis B and C exist only in man; the viruses have no known non-human reservoirs. Transmission of the viruses can be interrupted by vaccination against hepatitis B virus infection acid improvements in medical techniques for hepatitis C; for which no vaccine has yet been developed.