Genetic structure and rabies spread potential in raccoons: the role of landscape barriers and sex-biased dispersal
Genetic structure and rabies spread potential in raccoons: the role of landscape barriers and sex-biased dispersal
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DOI：
10.1111/j.1752-4571.2012.00238.x
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发表时间：
2012-06-01
影响因子：
4.1
通讯作者：
Pelletier, Fanie
中科院分区：
文献类型：
--
作者：
Cote, Heloise;Garant, Dany;Pelletier, Fanie
确定与传染病相关的宿主移动的自然障碍对于制定有效的控制战略至关重要。浣熊狂犬病变种（RRV）是一种引起人类关注的人畜共患病，因为其主要媒介浣熊（Procyon lotor）在居民区附近发现。在加拿大魁北克，自2006年以来在浣熊身上发现的所有RRV病例都是在黎塞留河的东侧发现的，这表明这条河是基因流动的障碍，因此RRV有可能传播。本研究的目的是描述浣熊种群的遗传结构，并评估黎塞留河对加拿大魁北克南部种群结构的影响。我们还评估了RRV传播潜力是否在性别和更大的空间尺度上存在差异。我们的分析显示，位于黎塞留河两侧的个体之间的遗传分化信号微弱。在更大的空间尺度上，遗传结构是薄弱的。我们的研究结果表明，河流可能并不总是有效地抑制浣熊的运动和RRV的传播。我们认为，在两性之间发现的遗传结构的差异可以部分解释男性运动在冬季繁殖季节，当冰桥允许通过在魁北克的大多数河流。
Identifying natural barriers to movements of hosts associated with infectious diseases is essential for developing effective control strategies. Raccoon rabies variant (RRV) is a zoonosis of concern for humans because its main vector, the raccoon (Procyon lotor), is found near residential areas. In Quebec, Canada, all cases of RRV found in raccoons since 2006 were detected on the eastern side of the Richelieu River, suggesting that this river acts as a barrier to gene flow and thus the potential for RRV to spread. The objectives of this study were to characterize the genetic structure of raccoon populations and assess the effect of the Richelieu River on the population structure in southern Quebec, Canada. We also evaluated whether RRV spread potential differed between sex and at a larger spatial scale. Our analyses revealed a weak signal of genetic differentiation among individuals located on each side of the Richelieu River. At a larger spatial scale, genetic structuring was weak. Our results suggest that rivers might not always efficiently restrain raccoon movements and spread of RRV. We suggest that the difference in genetic structure found between sexes can be partly explained by male movements during the breeding season in winter, when ice bridges allow passage over most rivers in Quebec.