Reductive cyclization of α-cyclopropylketones with alkynyl- and aryl-tethered substituents
Reductive cyclization of α-cyclopropylketones with alkynyl- and aryl-tethered substituents
复制标题
DOI：
10.1016/s0040-4020(98)00323-8
复制
发表时间：
1998-06-04
期刊：
影响因子：
2.1
通讯作者：
Mattay, J
中科院分区：
文献类型：
--
作者：
Fagnoni, M;Schmoldt, P;Mattay, J
利用α-环丙基取代酮与三乙胺(TEA)的光诱导电子转移(PET)反应引发环丙基卡宾-高烯丙基重排反应。在三键上进行分子内环化反应，得到双环和螺环化合物。此外，一些初步的研究表明，即使是分子内的芳香取代也是可行的。(C)1998爱思唯尔科学有限公司。保留所有权利。
Photoinduced electron transfer (PET) reactions of alpha-cyclopropyl-substituted ketones and triethylamine (TEA) were used to initiate the cyclopropylcarbinyl-homoallyl rearrangement. The intramolecular cyclization reaction onto triple bonds was performed yielding bicyclic and spirocyclic compounds. Furthermore, in some preliminary studies it was shown that even intramolecular aromatic substitutions are feasible. (C) 1998 Elsevier Science Ltd. All rights reserved.