Risk factors for severe hyperbilirubinemia in neonates
Risk factors for severe hyperbilirubinemia in neonates
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DOI：
10.1203/01.pdr.0000141846.37253.af
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发表时间：
2004-11-01
影响因子：
3.6
通讯作者：
Huang, CS
中科院分区：
文献类型：
--
作者：
Huang, MJ;Kua, KE;Huang, CS
严重新生儿高胆红素血症的发生率在亚洲人中高于白人。本研究旨在探讨八种已知的危险因子[母乳喂养、ABO血型不合、早产、感染、头血肿、窒息、葡萄糖-6-磷酸脱氢酶（G6 PD）缺乏症、变异型UDP-葡萄糖醛酸转移酶1A 1（UGT 1A 1）基因]和一种可疑的类似物[有机阴离子转运蛋白2（OATP 2）基因]对台湾新生儿重度高胆红素血症的影响。72名研究对象和100名医院对照对象包括血清胆红素峰值水平大于或等于342 μ M的新生儿，
The incidence of severe neonatal hyperbilirubinemia is higher in Asians than in whites. A case-control study was designed to investigate the effects of eight known risk factors [breast feeding, ABO incompatibility, premature birth, infection, cephalohema-toma, asphyxia, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and variant UDP-glucuronosyltransferase 1A1 (UGT1A1) gene] and a suspicious analog [organic anion transporter 2 (OATP 2) gene] on severe hyperbilirubinemia in Taiwanese neonates. The 72 study subjects and 100 hospital control subjects consisted of neonates with peak serum bilirubin levels greater than or equal to342 muM and