Anthropometric Charts for Infants Born Between 22 and 29 Weeks' Gestation
Anthropometric Charts for Infants Born Between 22 and 29 Weeks' Gestation
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DOI：
10.1542/peds.2016-1641
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发表时间：
2016-12-01
期刊：
影响因子：
8
通讯作者：
Horbar, Jeffrey D.
中科院分区：
文献类型：
--
作者：
Boghossian, Nansi S.;Geraci, Marco;Horbar, Jeffrey D.
目的：使用一个大型的、种族多样化的美国数据集，我们的主要目的是：（1）拟合和验证性别特异性出生体重和头围的胎龄图，用于22至29周妊娠出生的婴儿;（2）拟合种族特异性出生体重和头围的胎龄图。我们使用了2006年至2014年期间收集的183243例无先天性畸形的单胎婴儿的数据，这些婴儿的胎龄在22周0天和29周6天之间，来自佛蒙特州牛津网络的852名美国成员。对于性别特异性图表，最终样本量包括156587名出院存活的婴儿。从这156587名婴儿中，我们提取了47005名婴儿的子集，分别适合白色、黑人和亚洲婴儿的性别特异性图表。对于所有的图表，我们采用分位数回归模型来预测婴儿的出生体重和头围从胎龄表示days.RESULTS：我们成功地验证了整体性别特异性图表。在大多数的胎龄范围内，黑人婴儿，无论是女孩还是男孩，有最低的预测出生体重相比，白色和亚洲婴儿为许多fulles.CONCLUSIONS：我们拟合和验证新的性别特异性图表使用最近的，大的，和种族多样化的数据集。未来的步骤包括使用这些图表来检查出生时体重和头围与死亡率和发病率的关系。
OBJECTIVES: Using a large, racially diverse US dataset, we aimed primarily to: (1) fit and validate sex-specific birth weight and head circumference for gestational age charts for infants born at 22 to 29 weeks' gestation; and (2) fit race-specific birth weight and head circumference for gestational age charts.METHODS: We used data collected between 2006 and 2014 on 183 243 singleton infants without congenital malformations with gestational age between 22 weeks, 0 days and 29 weeks, 6 days from 852 US members of the Vermont Oxford Network. For the sex-specific charts, the final sample size included 156 587 infants who survived hospital discharge. From these 156 587, we abstracted a subset of 47 005 infants to fit sex-specific charts separately for white, black, and Asian infants. For all charts, we applied quantile regression models to predict infants' birth weight and head circumference percentiles from gestational age expressed in days.RESULTS: We successfully validated the overall sex-specific charts. Over most of the gestational age range, black infants, either girls or boys, had the lowest predicted birth weight as compared with white and Asian infants for many percentiles.CONCLUSIONS: We fitted and validated new sex-specific charts using a recent, large, and racially diverse dataset. Future steps include using these charts to examine associations of weight and head circumference at birth with mortality and morbidity.