Motoric Cognitive Risk Syndrome: Prevalence and Risk of Cognitive Impairment in a Population Studied in the Mexican Health and Aging Study 2012-2015
Motoric Cognitive Risk Syndrome: Prevalence and Risk of Cognitive Impairment in a Population Studied in the Mexican Health and Aging Study 2012-2015
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DOI：
10.1007/s12603-019-1160-7
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发表时间：
2019-03-01
影响因子：
5.8
通讯作者：
Mejia-Arango, S.
中科院分区：
文献类型：
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作者：
Aguilar-Navarro, S. G.;Mimenza-Alvarado, A. J.;Mejia-Arango, S.
目的本研究的目的是确定墨西哥老年人样本中运动认知风险 (MCR) 综合征的患病率，描述相关的危险因素，并确定三年随访后进展为认知障碍的风险。设计墨西哥健康与老龄化的前瞻性小组研究。设置和参与者基线和随访信息来自墨西哥健康与老龄化研究的 2012 年和 2015 年波次。总共 726 名 60 岁或以上、基线认知正常的受试者被分为 4 组：1）有 MCR，2）仅有记忆障碍，3）仅有慢步态，4）无 MCR。控制混杂因素后进行 Cox 回归分析，以确定 MCR 组进展为认知障碍的风险。收集了步态速度、功能状态和认知表现（按墨西哥人口年龄和性别标准化）等测量数据。结果 MCR 患病率为 14.3%。与非 MCR 受试者相比，MCR 的存在与年龄较大相关（p
ObjectivesThe aim of this study was to determine the prevalence of Motoric Cognitive Risk (MCR) syndrome, describe associated risk factors and to determine the risk of progression to cognitive impairment after three years of follow-up, in a sample of Mexican older adults.DesignA prospective panel study of health and aging in Mexico.Setting and participantsBaseline and follow-up information was obtained from the Mexican Health and Aging Study's 2012 and 2015 waves. A total of 726 subjects aged 60 years or older with normal cognition at baseline were classified into 4 groups: 1) with MCR, 2) with memory complaint only, 3) with slow gait speed only and, 4) without MCR. Cox regression analysis controlling for confounder factors was performed to determine the risk of progression to cognitive impairment in the MCR group.MeasuresData such as gait speed, functional status and cognitive performance (standardized by age and sex in Mexican population) was collected.ResultsMCR prevalence was 14.3%. When compared with non-MCR subjects, the presence of MCR was associated with older age (p