Chemoluminescence during ATP hydrolysis by rat brain ATPase under the influence of agents of a narcotic nature

Chemoluminescence during ATP hydrolysis by rat brain ATPase under the influence of agents of a narcotic nature
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发表时间:
1977
期刊:
Farmakologiia i toksikologiia
影响因子:
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通讯作者:
Vagin IuE;Kovrizhnykh Va
Vagin IuE;Kovrizhnykh Va
中科院分区:
其他
文献类型:
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作者:
Vagin IuE;Kovrizhnykh Va

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:在乙醚、硫喷妥钠和电诱导麻醉的大鼠中,研究了脑 ATP 酶的活性和脑 ATP 酶水解 ATP 时的化学发光。在乙醚麻醉中,ATP 酶活性和化学发光水平降低。在硫喷妥钠麻醉下,它们会增加,而在电诱导麻醉下,它们会先上升,然后下降。一旦研究药物的作用停止,上述参数就会恢复到其控制水平。
: The activity of the cerebral ATP-ase and chemoluminescence in hydrolysis of the ATP with the cerebral ATP-ase in rats with ether, thiopental and electrically-induced anesthesia was investigated. In the ether anesthesis the ATP-ase activity and the chemoluminescence level decrease. In the thiopental anesthesia they increase, whereas with electrically-induced one they first go up and then fall off. Once the action of the study agents is discontinued the mentioned parameters return back to their control levels.