Polybrominated diphenyl ethers and their hydroxylated analogs in plasma of bottlenose dolphins (Tursiops truncatus) from the United States east coast
Polybrominated diphenyl ethers and their hydroxylated analogs in plasma of bottlenose dolphins (Tursiops truncatus) from the United States east coast
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DOI：
10.1897/09-031.1
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发表时间：
2009-10
影响因子：
4.1
通讯作者：
M. Houde;G. Pacepavicius;C. Darling;P. Fair;M. Alaee;G. Bossart;K. Solomon;R. Letcher;A. Bergman;G. Marsh;D. Muir
中科院分区：
文献类型：
--
作者：
M. Houde;G. Pacepavicius;C. Darling;P. Fair;M. Alaee;G. Bossart;K. Solomon;R. Letcher;A. Bergman;G. Marsh;D. Muir
对来自南卡罗来纳州查尔斯顿 (CHS) 和美国佛罗里达州印第安河泻湖 (IRL) 的自由放养的宽吻海豚 (Tursiops truncatus) 血浆中的多溴二苯醚 (PBDE) 和羟基化 PBDE (OH-PBDE) 进行了测定。与来自 CHS 的动物（30 ± 40 ng/g 湿重）相比，来自 IRL 的动物（算术平均值为 5.45 ± 4.63 ng/g 湿重）的 PBDE 浓度总和 (Σ) 显着较低（12 个同系物的总和）。溴化二苯醚 (BDE)-47 是来自 IRL（占 ΣPBDE 的 50%）和 CHS（占 58%）的海豚中的主要 PBDE。在这两个地点，海豚血浆中的ΣPBDE浓度与年龄呈负相关。可以在 IRL 和 CHS 的海豚血浆中分别定量 15 种和 16 种 OH-PBDE 同系物。与 ΣPBDE 类似，CHS 海豚血浆中 ΣOH-PBDE 平均浓度（1,150 ± 708 pg/g 湿重）显着高于 IRL 海豚血浆中的平均 ΣOH-PBDE 浓度（624 ± 393 pg/g 湿重）。两个地点的主要同源物是 6-OH-PBDE-47（IRL，384 ± 319 pg/g 湿重；CHS，541 ± 344 pg/g 湿重），占 IRL 总 ΣOH-PBDE 的 61.5%，占 CHS 总 ΣOH-PBDE 的 47.0%。 ΣOH-PBDE 浓度与两个地点的海豚年龄呈弱负相关（p < 0.05；IRL，r2 = 0.048；CHS，r2 = 0.021）。除了技术标准鉴定出的 OH-PBDE 同系物外，在 CHS（未鉴定的 OH-PBDE 总和 = 1.35 ± 0.90 pg/g 湿重）和 IRL（0.73 ± 0.40 pg/g 湿重）的动物中分别检测到并定量了 8 种和 4 种未鉴定的 OH-PBDE。本研究的结果表明，与 OH-PCB 不同，宽吻海豚体内的 OH-PBDE 相对于 ΣPBDE 而言是血浆中的次要产物，并且很大一部分可能是通过饮食摄入天然产生的甲氧基化-PBDE 和 OH-PBDE 的结果。
Polybrominated diphenyl ethers (PBDEs) and hydroxylated PBDEs (OH‐PBDEs) were determined in plasma of freeranging bottlenose dolphins (Tursiops truncatus) from Charleston (CHS), South Carolina, and the Indian River Lagoon (IRL), Florida, USA. Significantly lower sums (Σ) of PBDE concentrations (sum of 12 congeners) were found in animals from the IRL (arithmetic mean, 5.45 ± 4.63 ng/g wet wt) compared with those from CHS (30 ± 40 ng/g wet wt). Brominated diphenyl ether (BDE)‐47 was the predominant PBDE in dolphins from the IRL (50% of the ΣPBDEs) and CHS (58%). The ΣPBDE concentrations in plasma of dolphins were negatively correlated with age at both locations. Fifteen and sixteen individual OH‐PBDE congeners could be quantified in plasma of dolphins from IRL and CHS, respectively. Similar to ΣPBDE, mean ΣOH‐PBDE concentrations were significantly higher in plasma of dolphins at CHS (1,150 ± 708 pg/g wet wt) compared with those at IRL (624 ± 393 pg/g wet wt). The predominant congener at both locations was 6‐OH‐PBDE‐47 (IRL, 384 ± 319 pg/g wet wt; CHS, 541 ± 344 pg/g wet wt), representing 61.5% of total ΣOH‐PBDE at IRL and 47.0% at CHS. Concentrations of ΣOH‐PBDEs were weakly negatively correlated with age in dolphins from both locations (p < 0.05; IRL, r2 = 0.048; CHS, r2 = 0.021). In addition to the OH‐PBDE congeners identified with technical standards, eight and four unidentified OH‐PBDEs were detected and quantified, respectively, in animals from CHS (sum of unidentified OH‐PBDEs = 1.35 ± 0.90 pg/g wet wt) and IRL (0.73 ± 0.40 pg/g wet wt). Results of the present study suggest that, unlike OH‐PCBs, OH‐PBDEs in bottlenose dolphins are minor products in plasma relative to ΣPBDEs and a significant proportion may be a consequence of the dietary uptake of naturally produced methoxylated‐ and OH‐PBDEs.