Imaging cortical anatomy by high-resolution MR at 3.0T: Detection of the stripe of Gennari in visual area 17
Imaging cortical anatomy by high-resolution MR at 3.0T: Detection of the stripe of Gennari in visual area 17
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DOI：
10.1002/mrm.10255
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发表时间：
2002-10-01
影响因子：
3.3
通讯作者：
Koretskyk, AP
中科院分区：
文献类型：
--
作者：
Barbier, EL;Marrett, S;Koretskyk, AP
大脑可以分成许多解剖和功能亚单位。Brodmann的经典作品（Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues. Leipzig：Barth; 1909）根据组织学差异确定了大脑皮层的区域。他的细胞结构方法的另一种选择是骨髓结构方法。由于髓磷脂的存在，MRI在大脑中具有极好的白色/灰质对比度，因此似乎特别适合于皮质脊髓结构的体内研究。在这里，它表明，条纹或纹的Gennari可以始终检测到人类枕叶皮层。10名正常志愿者中有6名在3 T条件下获得的T-1加权图像，分辨率为350 x 350 x 600 mu，清楚地显示了这一富含髓鞘的皮质内层。它的结论是，人类大脑的纹状皮质（区域17的布罗德曼）可以在体内划定的T-1加权图像，可能使检测特定的皮质边界内的个人大脑。出版2002 Wiley-Liss，Inc.
The brain can be parcellated into numerous anatomical and functional subunits. The classic work by Brodmann (Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues. Leipzig: Barth; 1909) identified areas of the cerebral cortex based on histological differences. An alternative to his cytoarchitectonic approach is the myeloarchitectonic approach. MRI has excellent white/gray matter contrast in the brain due to the presence of myelin, and thus seems uniquely suited for in vivo studies of cortical myeloarchitecture. Here it is demonstrated that the stripe or stria of Gennari can be consistently detected in human occipital cortex. T-1-weighted images obtained at 3T from six of 10 normal volunteers, with resolutions of 350 x 350 x 600 mu, clearly demonstrate this myelin-rich intracortical layer. It is concluded that the striate cortex (area 17 of Brodmann) of the human brain can be delineated in vivo on T-1-weighted images, potentially enabling detection of specific cortical boundaries within individual brains. Published 2002 Wiley-Liss, Inc.