New in vitro and in ex-vivo triple co-culture BBB models and in vivo EAE model revealed that NMO-IgG increased the intracerebral transferability of NMO-IgG and satralizumab and that IL-6 blockade suppressed the NMO-IgG-induced leukocyte transmigration and
New in vitro and in ex-vivo triple co-culture BBB models and in vivo EAE model revealed that NMO-IgG increased the intracerebral transferability of NMO-IgG and satralizumab and that IL-6 blockade suppressed the NMO-IgG-induced leukocyte transmigration and
复制标题
新的体外和离体三重共培养 BBB 模型和体内 EAE 模型表明,NMO-IgG 增加了 NMO-IgG 和 satralizumab 的脑内转移性,并且 IL-6 阻断抑制了 NMO-IgG 诱导的白细胞迁移和
DOI:
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发表时间:
2021
期刊:
影响因子:
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通讯作者:
Kanda T
中科院分区:
文献类型:
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作者:
Takeshita Y;Fujikawa S;Serizawa K;Fujisawa M;Matsuo K;Nemoto J;Shimizu F;Sano Y;Tomizawa-Shinohara H;Miyake S;Ransohoff RM;Kanda T