Depression in rheumatoid arthritis patients: demographic, clinical, and psychological predictors
Depression in rheumatoid arthritis patients: demographic, clinical, and psychological predictors
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DOI：
10.1016/j.jpsychores.2005.09.011
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发表时间：
2006-05-01
影响因子：
4.7
通讯作者：
Howe, Graydon
中科院分区：
文献类型：
--
作者：
Covic, Tanya;Tyson, Graham;Howe, Graydon
目的：确定类风湿关节炎(RA)患者中抑郁的患病率，找出RA患者中抑郁的最显著预测因素，并探讨患者对与抑郁有关的药物治疗的态度。方法：采用横断面调查方法收集134例RA患者(女性77%，男性23%)的资料。参与者根据他们在流行病学研究中心抑郁量表(CES-D)上的得分被分为抑郁组和非抑郁组。进行判别分析，以确定将患者最好地归类到这两组中的预测因素。结果：12个预测者正确地将80%的患者分为抑郁组和非抑郁组。抑郁的最强预测因素是高度紧张和低自尊，其次是RA的感知影响、疲劳、被动应对、疼痛和身体残疾。其他预测因素包括药物的有效性和重要性，以及感觉到的对疼痛的缺乏控制。结论：躯体因素和心理因素对RA患者的抑郁均有影响。这项研究中确定的关键预测因素需要在常规RA管理中考虑为抑郁症发展的可能线索。(C)2006 Elsevier Inc.保留所有权利。
Objective: To confirm the prevalence of depression in a sample of rheumatoid arthritis (R-A) patients; to identify the most significant predictors of depression in RA and to explore patients attitudes to medication in relation to depression. Methods: A cross-sectional survey was used to collect data from 134 RA patients (77% female, 23% male). Participants were divided into depressed and nondepressed groups based on their scores on the Center for Epidemiological studies-Depression (CES-D) scale. Discriminant analysis was conducted to identify, the predictors that would best categorise patients into those two groups. Results: Twelve predictors correctly classified 80% of patients into depressed or nondepressed groups. The strongest predictors of depression were high tension and low self-esteem followed by the perceived impact of RA, fatigue, passive coping, pain, and physical disability. Other predictors included medication effectiveness and importance as well as perceived lack of control over pain. Conclusion: Both physical and psychological factors have an impact on depression in RA. The key predictors identified in this study need to be considered within the regular RA management as possible cues to depression development. (c) 2006 Elsevier Inc. All rights reserved.