Metal-Free One-Pot Oxidative Amidation of Aldoses with Functionalized Amines

Metal-Free One-Pot Oxidative Amidation of Aldoses with Functionalized Amines
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DOI:
10.1021/jo801626v
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发表时间:
2008-11-07
影响因子:
3.6
通讯作者:
Martin, Olivier R.
Martin, Olivier R.
中科院分区:
化学2区
文献类型:
--
作者:
Colombeau, Ludovic;Traore, Tenin;Martin, Olivier R.

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使用碘的醛糖与功能化胺的无金属一锅氧化酰胺可快速访问功能化的醛氨酰胺。这种方法的主要优点取决于以下事实:醛氧化和C-N键形成是在单个合成操作中进行的。
Metal-free one-pot oxidative amidation of aldoses with functionalized amines using iodine provides a rapid access to functionalized aldonamides. The main advantage of this approach relies on the fact that aldehyde oxidation and C-N bond formation are performed in a single synthetic operation.