A meta-analysis of the relationship between anxiety and telomere length
A meta-analysis of the relationship between anxiety and telomere length
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DOI：
10.1080/10615806.2016.1261286
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发表时间：
2017-01-01
影响因子：
3.7
通讯作者：
Schutte, Nicola S.
中科院分区：
文献类型：
--
作者：
Malouff, John M.;Schutte, Nicola S.
背景与目的：端粒是染色体末端的保护帽，较短的端粒与身体健康状况差有关。本研究的目的是巩固不同的影响大小的研究中发现到目前为止，焦虑和端粒长度。设计和方法：焦虑和端粒长度之间的关系的荟萃分析调查使用的信息从17个不同的样本，包括共19,424 participator.Results：结果显示，一个小的，但显着的关联，r=-.06，更高的焦虑和更短的端粒之间。研究比较诊断为焦虑症的个人与其他个人有显着的效果大小，和研究，不使用这个比较阈值没有显着的效果大小。结论：焦虑与健康相关的一个重要的生物标志物。未来的实验研究，旨在减少焦虑的干预措施的影响，结合端粒长度的测量，可以进一步澄清焦虑对端粒长度的影响。
Background and objectives: Telomeres are protective caps at the ends of chromosomes, and shorter telomeres are associated with poor physical health. The present study set out to consolidate the varying effect sizes found so far in studies of anxiety and telomere length.Design and methods: A meta-analytic investigation of the relationship between anxiety and telomere length used information from 17 different samples comprising a total of 19,424 participants.Results: The results showed a small but significant association, r=-.06, between higher anxiety and shorter telomeres. Studies comparing individuals diagnosed with an anxiety disorder with other individuals had a significant effect size, and studies that did not use this comparison threshold did not have a significant effect size.Conclusions: Anxiety is associated with an important biomarker related to health. Future experimental studies that examine the impact of interventions intended to reduce anxiety in conjunction with measurement of telomere length can further clarify the impact of anxiety on telomere length.