UniProt: the Universal Protein knowledgebase
UniProt: the Universal Protein knowledgebase
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DOI：
10.1093/nar/gkh131
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发表时间：
2004-01-01
影响因子：
14.9
通讯作者：
Yeh, LSL
中科院分区：
文献类型：
--
作者：
Apweiler, R;Bairoch, A;Yeh, LSL
为了向科学界提供一个单一的、集中的、权威的蛋白质序列和功能信息资源，SwissProt、TrEMBL和PIR蛋白质数据库活动联合起来形成了通用蛋白质知识库（UniProt）联盟。我们的使命是提供一个全面的，完全分类的，丰富和准确注释的蛋白质序列知识库，具有广泛的交叉引用和查询接口。中央数据库将有两个部分，分别对应于熟悉的SwissProt（完全手动管理的条目）和TrEMBL（通过自动分类、注释和广泛的交叉引用而丰富）。为了方便序列搜索，UniProt还提供了几个非冗余序列数据库。UniProt NREF（UniRef）数据库提供了适用于高效搜索的知识库的代表性子集。综合的UniProt档案（UniParc）每天从许多公共源数据库更新。UniProt数据库可在线访问（www.uniprot.org）或以多种格式下载（ftp：//ftp.uniprot.org/pub）。鼓励科学界提交数据，以便纳入UniProt。
To provide the scientific community with a single, centralized, authoritative resource for protein sequences and functional information, the SwissProt, TrEMBL and PIR protein database activities have united to form the Universal Protein Knowledgebase (UniProt) consortium. Our mission is to provide a comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive cross-references and query interfaces. The central database will have two sections, corresponding to the familiar SwissProt (fully manually curated entries) and TrEMBL (enriched with automated classification, annotation and extensive cross-references). For convenient sequence searches, UniProt also provides several non-redundant sequence databases. The UniProt NREF (UniRef) databases provide representative subsets of the knowledgebase suitable for efficient searching. The comprehensive UniProt Archive (UniParc) is updated daily from many public source databases. The UniProt databases can be accessed online (http://www.uniprot.org) or downloaded in several formats (ftp://ftp.uniprot.org/pub). The scientific community is encouraged to submit data for inclusion in UniProt.